In silico screening and molecular docking of flavonoids against the Alzheimer's disease using ACHE, BACE1 and tau protein targets

被引：0
|
作者：
Sree, D. Ramya [1 ]
Boyina, Hemanthkumar [2 ]
机构：
[1] Anurag Univ, Dept Pharmacol, Hyderabad, India
[2] Anurag Univ, Sch Pharm, Dept Pharmacol, Hyderabad, Telangana, India
来源：
JOURNAL OF THE NEUROLOGICAL SCIENCES | 2023年 / 455卷
关键词：
D O I：
10.1016/j.jns.2023.122116
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
122116
引用
收藏
页数：1
相关论文
共 50 条
  • [21] Exploring the Benzazoles Derivatives as Pharmacophores for AChE, BACE1, and as Anti-Aβ Aggregation to Find Multitarget Compounds against Alzheimer's Disease
    Hernandez, Martha Cecilia Rosales
    Olvera-Valdez, Marycruz
    Toledano, Jazziel Velazquez
    Wejebe, Jessica Elena Mendieta
    Morales, Leticia Guadalupe Fragoso
    Cruz, Alejandro
    MOLECULES, 2024, 29 (19):
  • [22] Identification of potential lead compounds against BACE1 through in-silico screening of phytochemicals of Medhya rasayana plants for Alzheimer's disease management
    Nadh, Anuroopa G.
    Revikumar, Amjesh
    Sudhakaran, P. R.
    Nair, Achuthsankar S.
    COMPUTERS IN BIOLOGY AND MEDICINE, 2022, 145
  • [23] Dual Inhibitors of AChE and BACE-1 for Reducing Aβ in Alzheimer's Disease: From In Silico to In Vivo
    Stern, Noa
    Gacs, Alexandra
    Tatrai, Eniko
    Flachner, Beata
    Hajdu, Istvan
    Dobi, Krisztina
    Bagyi, Istvan
    Dorman, Gyorgy
    Lorincz, Zsolt
    Cseh, Sandor
    Kigyos, Attila
    Tovari, Jozsef
    Goldblum, Amiram
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (21)
  • [24] BACE1 and BACE2 enzymatic activities in Alzheimer's disease
    Ahmed, Rachel R.
    Holler, Christopher J.
    Webb, Robin L.
    Li, Feng
    Beckett, Tina L.
    Murphy, M. Paul
    JOURNAL OF NEUROCHEMISTRY, 2010, 112 (04) : 1045 - 1053
  • [25] Machine learning models for predicting the activity of AChE and BACE1 dual inhibitors for the treatment of Alzheimer's disease
    Dhamodharan, G.
    Mohan, C. Gopi
    MOLECULAR DIVERSITY, 2022, 26 (03) : 1501 - 1517
  • [26] In-silico docking and molecular dynamic introspective study of multiple targets of AChE with Rivastigmine and NMDA receptors with Riluzole for Alzheimer's disease
    Chintha, Narendar
    Jupudi, Srikanth
    Palathoti, Nagarjuna
    Bharathi, J. Jeyaram
    Justin, Antony
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 41 (22): : 12620 - 12631
  • [27] Machine learning models for predicting the activity of AChE and BACE1 dual inhibitors for the treatment of Alzheimer’s disease
    G. Dhamodharan
    C. Gopi Mohan
    Molecular Diversity, 2022, 26 : 1501 - 1517
  • [28] The potential for BACE1 inhibitors in the treatment of Alzheimer's disease
    Hussain, I
    IDRUGS, 2004, 7 (07) : 653 - 658
  • [29] Molecular Regulaion of BACE1 and Its Function at The Early Onset of Alzheimer's Disease
    Wang Tan
    Sun Xiu-Lian
    PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2012, 39 (08) : 709 - 714
  • [30] BACE1 structure and function in health and Alzheimer's disease
    Cole, Sarah L.
    Vassar, Roger
    CURRENT ALZHEIMER RESEARCH, 2008, 5 (02) : 100 - 120
12345