ApoE isoforms alter glial Nrf2 activation, and antioxidant levels and oxidative damage in cerebral cortex of mice and humans

被引:0
|
作者
Thorwald, Max [1 ]
Shemtov, Sarah [1 ]
Godoy-Lugo, Jose [1 ]
Vermulst, Marc [1 ]
Forman, Henry [2 ]
Finch, Caleb [3 ]
机构
[1] Univ Southern Calif, Leonard Davis Sch Gerontol, Los Angeles, CA 90007 USA
[2] Univ Southern Calif, Studio City, CA USA
[3] Univ Southern Calif, Los Angeles, CA 90007 USA
关键词
D O I
10.1016/j.freeradbiomed.2023.10.377
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
365
引用
收藏
页码:S165 / S166
页数:2
相关论文
共 50 条
  • [41] Oxidative Stress and Activation of Nrf2 Precedes the Pathogenic Transition of Reductive Stress-Induced Cardiomyopathy in Mice
    Soorappan, Rajasekaran Namakkal
    Varadharaj, Saradhadevi
    Khanderao, Gayatri Deepti
    Davidson, Christopher J.
    Zweier, Jay L.
    Benjamin, Ivor J.
    FREE RADICAL BIOLOGY AND MEDICINE, 2009, 47 : S65 - S65
  • [42] Sulforaphane Prevents Testicular Damage in Kunming Mice Exposed to Cadmium via Activation of Nrf2/ARE Signaling Pathways
    Yang, Shu-Hua
    Long, Miao
    Yu, Li-Hui
    Li, Lin
    Li, Peng
    Zhang, Yi
    Guo, Yang
    Gao, Feng
    Liu, Ming-Da
    He, Jian-Bin
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2016, 17 (10):
  • [43] Upregulation of antioxidant and autophagy pathways via NRF2 activation protects spinal cord neurons from ozone damage
    Zhang, Cong
    Ma, Shulin
    Zhao, Xu
    Wen, Bei
    Sun, Panpan
    Fu, Zhijian
    MOLECULAR MEDICINE REPORTS, 2021, 23 (06)
  • [44] Dietary prenylated flavonoid xanthohumol alleviates oxidative damage and accelerates diabetic wound healing via Nrf2 activation
    Lu, Xuxiu
    Liu, Mingfei
    Dong, Hui
    Miao, Jinlai
    Stagos, Dimitrios
    Liu, Ming
    FOOD AND CHEMICAL TOXICOLOGY, 2022, 160
  • [45] DHA restores VEGF via Nrf2 protection pathway inhibiting oxidative damage in RPE at high glucose levels
    Johnsen-Soriano, Siv
    Arnal, Emma
    Flores-Bellver, Miguel
    Bonet-Ponce, Luis
    Romero, Francisco Javier
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2013, 54 (15)
  • [46] Proanthocyanidins Attenuation of Chronic Lead-Induced Liver Oxidative Damage in Kunming Mice via the Nrf2/ARE Pathway
    Long, Miao
    Liu, Yi
    Cao, Yu
    Wang, Nan
    Dang, Meng
    He, Jianbin
    NUTRIENTS, 2016, 8 (10):
  • [47] NOX2 ACTIVATION AND OXIDATIVE DAMAGE OF CEREBRAL VASCULATURE AND LOCOMOTOR FUNCTION IN AGEING MICE
    Geng, Li
    Cahill-Smith, Sarah
    Li, Jian-Mei
    HEART, 2014, 100 : A105 - A106
  • [48] Antioxidant and hepatoprotective effect of polyphenols from apple pomace extract via apoptosis inhibition and Nrf2 activation in mice
    Sharma, S.
    Rana, S.
    Patial, V.
    Gupta, M.
    Bhushan, S.
    Padwad, Y. S.
    HUMAN & EXPERIMENTAL TOXICOLOGY, 2016, 35 (12) : 1264 - 1275
  • [49] Lycopene attenuates AFB1-induced renal injury with the activation of the Nrf2 antioxidant signaling pathway in mice
    Yu, Kaiyuan
    Zhang, Jian
    Cao, Zheng
    Ji, Qiang
    Han, Yanfei
    Song, Miao
    Shao, Bing
    Li, Yanfei
    FOOD & FUNCTION, 2018, 9 (12) : 6428 - 6435
  • [50] Acacetin exerts antioxidant potential against atherosclerosis through Nrf2 pathway in apoE-/- mice (vol 25, pg 521, 2021)
    Wu, Y.
    Song, F.
    Li, Y.
    JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2024, 28 (20)