DMF as an amine source: iron-catalyzed cyclization of 2H-azirines to imidazoles

被引：1
|
作者：
Zhao, Mi-Na [1 ]
Yang, Zi-Mo [2 ]
Li, Lian-Qing [1 ]
机构：
[1] Shaanxi Xueqian Normal Univ, Coll Chem & Chem Engn, Xian 710100, Shaanxi, Peoples R China
[2] Baoji Univ Arts & Sci, Coll Chem & Chem Engn, Shaanxi Key Lab Phytochem, Baoji 721013, Shaanxi, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2024年 / 60卷 / 14期
基金：
中国国家自然科学基金;
关键词：
CYCLOADDITION; ACCESS; CHLORIDES; PYRROLES;
D O I：
10.1039/d3cc06147g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel method has been developed for the synthesis of 1-methyl4,5-diaryl-1H-imidazoles through Fe(II)-catalyzed cyclization of 2H-azirines and N,N-dimethylformamide (DMF) as an amine source. This transformation involves the cleavage of C-N and C=N double bonds and the construction of new C-N and C=N double bonds. The reaction has readily available starting materials, a wide range of substrates and mild reaction conditions. In addition, the reaction also facilitated the convenient synthesis of 1-methyl-2,4,5-triaryl1H-imidazoles.
引用
收藏
页码：1904 / 1907
页数：4
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