Harnessing immune checkpoint trial data in pediatric cancer

被引：0

作者：

Neeson, Paul J. ^{[1
,2
]}

Ekert, Paul G. ^{[1
,2
,3
,4
,5
]}

机构：

[1] Peter MacCallum Canc Ctr, Canc Immunol Program, Melbourne, Vic, Australia

[2] Univ Melbourne, Sir Peter MacCallum Dept Oncol, Melbourne, Vic, Australia

[3] Murdoch Childrens Res Inst, Parkville, Vic, Australia

[4] UNSW Sydney, Childrens Canc Inst, Lowy Canc Res Ctr, Kensington, NSW, Australia

[5] UNSW Sydney, Sch Clin Med, UNSW Med & Hlth, Sydney, NSW, Australia

来源：

NATURE CANCER | 2023年 / 4卷 / 04期

关键词：

SINGLE-ARM; OPEN-LABEL; PEMBROLIZUMAB; PROFILE; TUMOR;

D O I：

10.1038/s43018-023-00540-z

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The response rates of pediatric cancers to immune checkpoint inhibitor therapies are disappointingly low, particularly when compared to the remarkable impact of these drugs in many adult cancers. A new study leverages clinical trial data to identify biomarkers that might improve patient selection in future clinical trials.

引用

页码：444 / 446

页数：3

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