Hepatic soluble epoxide hydrolase A promising target for unveiling the liver-brain axis in Alzheimer's disease

被引：1
|
作者：
Inoue, Yasuteru [1 ]
Bamkole, Michael [1 ]
Kanekiyo, Takahisa [1 ]
机构：
[1] Mayo Clin, Dept Neurol, Jacksonville, FL 32224 USA
来源：
NEURON | 2023年 / 111卷 / 18期
关键词：
PATHOLOGY;
D O I：
10.1016/j.neuron.2023.08.019
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Wu and Dong et al.(1) report that hepatic soluble epoxide hydrolase (sEH) manipulation impacts amyloid-beta (A beta) deposits and cognitive impairment in mouse models for Alzheimer's disease (AD), suggesting that hepatic sEH activity is a promising therapeutic target to treat AD.
引用
收藏
页码：2775 / 2777
页数：3
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