The Potential Use of Near- and Mid-Infrared Spectroscopy in Kidney Diseases

被引：4

作者：

Delrue, Charlotte ^{[1
]}

De Bruyne, Sander ^{[2
]}

Speeckaert, Marijn M. ^{[1
,3
]}

机构：

[1] Ghent Univ Hosp, Dept Nephrol, B-9000 Ghent, Belgium

[2] Ghent Univ Hosp, Dept Diagnost Sci, B-9000 Ghent, Belgium

[3] Res Fdn Flanders FWO, B-1000 Brussels, Belgium

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2023年 / 24卷 / 07期

关键词：

infrared spectroscopy; mid-infrared; near-infrared; attenuated total reflectance-Fourier-transform infrared spectroscopy; kidney diseases; NEAR-INFRARED SPECTROSCOPY; STAGE RENAL-DISEASE; VIBRATIONAL SPECTROSCOPY; CARDIAC-SURGERY; RISK-FACTORS; LIVE CELLS; UREA; INJURY; HEMODIALYSIS; DIAGNOSIS;

D O I：

10.3390/ijms24076740

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Traditional renal biomarkers such as serum creatinine and albuminuria/proteinuria are rather insensitive since they change later in the course of the disease. In order to determine the extent and type of kidney injury, as well as to administer the proper therapy and enhance patient management, new techniques for the detection of deterioration of the kidney function are urgently needed. Infrared spectroscopy is a label-free and non-destructive technique having the potential to be a vital tool for quick and inexpensive routine clinical diagnosis of kidney disorders. The aim of this review is to provide an overview of near- and mid-infrared spectroscopy applications in patients with acute kidney injury and chronic kidney disease (e.g., diabetic nephropathy and glomerulonephritis).

引用

页数：19

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