New Perspectives on Food Matrix Modulation of Food Allergies: Immunomodulation and Component Interactions

被引：4

作者：

Wu, Huan ^{[1
,2
,3
]}

Chen, Bihua ^{[1
,2
,3
]}

Wu, Yuhong ^{[1
,2
,3
]}

Gao, Jinyan ^{[1
,2
,3
]}

Li, Xin ^{[1
,2
,3
]}

Tong, Ping ^{[1
,3
]}

Wu, Yong ^{[1
,3
,4
]}

Meng, Xuanyi ^{[1
,3
,4
]}

Chen, Hongbing ^{[1
,3
,4
]}

机构：

[1] Nanchang Univ, State Key Lab Food Sci & Resources, Nanchang 330047, Peoples R China

[2] Nanchang Univ, Coll Food Sci & Technol, Nanchang 330031, Peoples R China

[3] Nanchang Univ, Jiangxi Prov Key Lab Food Allergy, Nanchang 330047, Peoples R China

[4] Nanchang Univ, Sino German Joint Res Inst, Nanchang 330047, Peoples R China

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2023年 / 71卷 / 36期

基金：

中国国家自然科学基金;

关键词：

food allergy; food matrix; matrix components; component interactions; immune response; ARA H 1; MAILLARD REACTION; EGG-WHITE; ALLERGENIC PROPERTIES; ALPHA-LACTALBUMIN; ORAL TOLERANCE; MAST-CELLS; N-GLYCANS; PROTEINS; POLYPHENOLS;

D O I：

10.1021/acs.jafc.3c03192

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

Food allergy is a multifactorial interplay process influenced not only by the structure and function of the allergen itself but also by other components of the food matrix. For food, before it is thoroughly digested and absorbed, numerous factors make the food matrix constantly change. This will also lead to changes in the chemistry, biochemical composition, and structure of the various components in the matrix, resulting in multifaceted effects on food allergies. In this review, we reveal the relationship between the food matrix and food allergies and outline the immune role of the components in the food matrix, while highlighting the ways and pathways in which the components in the food matrix interact and their impact on food allergies. The in-depth study of the food matrix will essentially explore the mechanism of food allergies and bring about new ideas and breakthroughs for the prevention and treatment of food allergies.

引用

页码：13181 / 13196

页数：16

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