Low mortality rate in a large cohort of myelin oligodendrocyte glycoprotein antibody disease (MOGAD)

被引:3
|
作者
Lotan, Itay [1 ]
Romanow, Gabriela [1 ]
Salky, Rebecca [1 ]
Molazadeh, Negar [1 ]
Vishnevetsky, Anastasia [1 ]
Anderson, Monique [1 ]
Bilodeau, Phillipe-Antoine [1 ]
Cutter, Gary [2 ]
Levy, Michael [1 ]
机构
[1] Harvard Med Sch, Massachusetts Gen Hosp, Dept Neurol, Neuroimmunol Clin & Res Lab, Boston, MA 02115 USA
[2] Univ Alabama Birmingham, Sch Publ Hlth, Birmingham, AL USA
来源
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY | 2023年 / 10卷 / 04期
关键词
OPTICA SPECTRUM DISORDERS; NEUROMYELITIS-OPTICA; CLINICAL SPECTRUM; ADULTS; AUTOIMMUNITY; AQUAPORIN-4;
D O I
10.1002/acn3.51750
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The mortality rates of individuals with myelin oligodendrocyte glycoprotein antibody disease (MOGAD) are currently unknown. This study aimed to assess the mortality rate in a large cohort of patients with MOGAD. Since none of the patients in our cohort died, we estimated the upper limit of a 95% confidence interval of the crude mortality rate in the cohort to be 2.1%. These data suggest that mortality in MOGAD is lower than that reported in other neuroinflammatory diseases and comparable to the age-adjusted mortality rates of the general population in the United States. Additional studies are warranted to confirm this observation.
引用
收藏
页码:664 / 667
页数:4
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