Low mortality rate in a large cohort of myelin oligodendrocyte glycoprotein antibody disease (MOGAD)

被引：3

作者：

Lotan, Itay ^{[1
]}

Romanow, Gabriela ^{[1
]}

Salky, Rebecca ^{[1
]}

Molazadeh, Negar ^{[1
]}

Vishnevetsky, Anastasia ^{[1
]}

Anderson, Monique ^{[1
]}

Bilodeau, Phillipe-Antoine ^{[1
]}

Cutter, Gary ^{[2
]}

Levy, Michael ^{[1
]}

机构：

[1] Harvard Med Sch, Massachusetts Gen Hosp, Dept Neurol, Neuroimmunol Clin & Res Lab, Boston, MA 02115 USA

[2] Univ Alabama Birmingham, Sch Publ Hlth, Birmingham, AL USA

来源：

ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY | 2023年 / 10卷 / 04期

关键词：

OPTICA SPECTRUM DISORDERS; NEUROMYELITIS-OPTICA; CLINICAL SPECTRUM; ADULTS; AUTOIMMUNITY; AQUAPORIN-4;

D O I：

10.1002/acn3.51750

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The mortality rates of individuals with myelin oligodendrocyte glycoprotein antibody disease (MOGAD) are currently unknown. This study aimed to assess the mortality rate in a large cohort of patients with MOGAD. Since none of the patients in our cohort died, we estimated the upper limit of a 95% confidence interval of the crude mortality rate in the cohort to be 2.1%. These data suggest that mortality in MOGAD is lower than that reported in other neuroinflammatory diseases and comparable to the age-adjusted mortality rates of the general population in the United States. Additional studies are warranted to confirm this observation.

引用

页码：664 / 667

页数：4

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