pH modulates the role of SP6 RNA polymerase in transcription process: an in silico study

被引：1

作者：

Singh, Satya Ranjan ^{[1
]}

Murali, Ayaluru ^{[1
]}

机构：

[1] Pondicherry Univ, Dept Bioinformat, Pondicherry, India

来源：

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS | 2023年 / 41卷 / 21期

关键词：

SP6 RNA polymerase; pH-based MD simulation; SP6; promoter; transcription; MM; PBSA; SINGLE-CRYSTALS; PROTEIN; BACTERIOPHAGES; SYSTEM; SPECIFICITY; INITIATION; MECHANISM; SEQUENCE; DYNAMICS; THERAPY;

D O I：

10.1080/07391102.2023.2170916

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The PRL and PBL of polymerase maintain a minimum distance from the promoter site at pH 7.9, leading to a possible transcription model for SP6 bacteriophage.

引用

页码：11763 / 11780

页数：18

共 50 条

[21] RAPID RNA SEQUENCING USING DOUBLE-STRANDED TEMPLATE DNA, SP6 POLYMERASE, AND 3'-DEOXYNUCLEOTIDE TRIPHOSPHATES
PARVIN, JD
SMITH, FI
PALESE, P
DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY, 1986, 5 (02): : 167 - 171
[22] 2 NEW PROMOTERS FOR SP6 PHAGE RNA-POLYMERASE ARE LOCALIZED IN THE HIND III-C DNA FRAGMENT DOWNSTREAM OF RNA-POLYMERASE GENE
SAVCHENKO, RS
ZHELEZNAIA, LA
DOLGIKH, DA
MATVIENKO, NI
DOKLADY AKADEMII NAUK SSSR, 1988, 300 (03): : 736 - &
[23] DNA INSERTED 2 BASES DOWN FROM THE INITIATION SITE OF A SP6 POLYMERASE TRANSCRIPTION VECTOR IS TRANSCRIBED EFFICIENTLY INVITRO
BUJARSKI, JJ
KAESBERG, P
NUCLEIC ACIDS RESEARCH, 1987, 15 (03) : 1337 - 1337
[24] The Role of Human Spt6 in Transcription Regulation by RNA Polymerase II
Fusby, B.
Bentley, D.
MOLECULAR BIOLOGY OF THE CELL, 2011, 22
[25] A role for β-actin in RNA polymerase III transcription
Hu, P
Wu, S
Hernandez, N
GENES & DEVELOPMENT, 2004, 18 (24) : 3010 - 3015
[26] The role of TAFs in RNA polymerase II transcription
Hahn, S
CELL, 1998, 95 (05) : 579 - 582
[27] FUNCTIONAL MESSENGER-RNAS ARE PRODUCED BY SP6 INVITRO TRANSCRIPTION OF CLONED CDNAS
KRIEG, PA
MELTON, DA
NUCLEIC ACIDS RESEARCH, 1984, 12 (18) : 7057 - 7070
[28] The Histidine-805 in motif-C of the phage SP6 RNA polymerase is essential for its activity as revealed by random mutagenesis
Jeong, W
Kang, CW
BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL, 1997, 42 (04): : 711 - 716
[29] Transcription through the roadblocks:: the role of RNA polymerase cooperation
Epshtein, V
Toulmé, F
Rahmouni, AR
Borukhov, S
Nudler, E
EMBO JOURNAL, 2003, 22 (18): : 4719 - 4727
[30] Role of RNA Polymerase and Transcription in the Organization of the Bacterial Nucleoid
Jin, Ding Jun
Cagliero, Cedric
Zhou, Yan Ning
CHEMICAL REVIEWS, 2013, 113 (11) : 8662 - 8682

← 1 2 3 4 5 →