pH modulates the role of SP6 RNA polymerase in transcription process: an in silico study

被引：1

作者：

Singh, Satya Ranjan ^{[1
]}

Murali, Ayaluru ^{[1
]}

机构：

[1] Pondicherry Univ, Dept Bioinformat, Pondicherry, India

来源：

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS | 2023年 / 41卷 / 21期

关键词：

SP6 RNA polymerase; pH-based MD simulation; SP6; promoter; transcription; MM; PBSA; SINGLE-CRYSTALS; PROTEIN; BACTERIOPHAGES; SYSTEM; SPECIFICITY; INITIATION; MECHANISM; SEQUENCE; DYNAMICS; THERAPY;

D O I：

10.1080/07391102.2023.2170916

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The PRL and PBL of polymerase maintain a minimum distance from the promoter site at pH 7.9, leading to a possible transcription model for SP6 bacteriophage.

引用

页码：11763 / 11780

页数：18

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