Green Synthesis of Metal Oxide Nanoparticles: a Novel Approach to Treat Diabetes Mellitus

被引:1
|
作者
Gaikwad, Shubhangee [1 ,3 ]
Vora, Shruti [2 ]
Bansode, Amol [1 ]
Garje, Vishal [2 ]
Bhaiya, Saurabh [2 ]
Choudhari, Vishnu [3 ]
机构
[1] Sinhgad Inst Pharm, Dept Pharmaceut Chem, Pune 411041, Maharashtra, India
[2] Sinhgad Inst Pharm, Dept Pharmaceut Qual Assurance, Pune 411041, Maharashtra, India
[3] WPU, Maharashtra Inst Pharm, MAEER, Sch Pharm, MIT Campus,Paud Rd Kothrud, Pune 411041, Maharashtra, India
关键词
Diabetes mellitus; Metal oxide nanoparticles; In-vitro studies; In-vivo studies; Anti-diabetic; Green synthesis; ANTIDIABETIC ACTIVITY; SILVER NANOPARTICLES; ZINC-OXIDE; GOLD NANOPARTICLES; CERIUM OXIDE; IN-VITRO; ANTIOXIDANT; EXTRACT;
D O I
10.1007/s12668-023-01205-y
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
Diabetes mellitus is a metabolic disorder in which a person fails to produce adequate insulin or insulin reactions to cells, so that blood sugar levels are high in diabetes patients. Nanoparticles of small particle size have very significant effects against other types of dosage. Diabetes is treated with metal oxide-like nanoparticles such as zinc oxide, silver oxide, cerium oxide, magnesium oxide, vanadium oxide, chromium oxide, and gold nanoparticles. Different plants are used for the green synthesis of zinc, silver, magnesium oxide, cerium oxide, and golden nanoparticles. These analyses include separate in vitro and in vivo tests. The in vitro studies include nanoparticles characterization, antioxidant studies, anti-diabetic studies, and green synthesized nanoparticles phytochemical studies. In the in vivo trials, the animal research involves a range of test models, diabetes induction, experimental design, sample collection, and blood sample characterization by different testing methods. Studies in in vitro and in vivo reveal nanoparticles of metal oxide to be anti-diabetic.
引用
收藏
页码:1582 / 1592
页数:11
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