Synergistic effects of TPP1 promoter mutations and TERT promoter mutations on telomere maintenance and immortalization in melanoma

被引:0
|
作者
Chun-on, P. [1 ,2 ,3 ]
Hinchie, A. M. [2 ]
Beale, H. C. [4 ]
Silva, A. A. G. [2 ]
Rush, E. [5 ]
Sander, C. [5 ]
Connelly, C. J. [6 ]
Seynnaeve, B. K. N. [5 ,7 ]
Kirkwood, J. M. [5 ]
Vaske, O. M. [8 ,9 ]
Greider, C. W. [6 ,9 ]
Alder, J. K. [2 ]
机构
[1] Univ Pittsburgh, Environm & Occupat Hlth, Sch Publ Hlth, Pittsburgh, PA USA
[2] Dorothy P & Richard P Simmons Ctr Interstitial Lu, Div Pulm Allergy & Crit Care Med, Pittsburgh, PA USA
[3] Chulabhorn Royal Acad, Fac Med & Publ Hlth, HRH Princess Chulabhorn Coll Med Sci, Bangkok, Thailand
[4] Univ Calif Santa Cruz, Environm & Occupat Hlth, Genom Inst, Santa Cruz, CA USA
[5] Univ Pittsburgh, Hillman Canc Ctr, Med Ctr, Pittsburgh, PA USA
[6] Johns Hopkins Univ, Dept Mol Biol & Genet, Sch Med, Baltimore, MD USA
[7] Univ Pittsburgh, Dept Pediat, Div Pediat Hematol Oncol, Sch Med, Pittsburgh, PA USA
[8] Univ Calif Santa Cruz, Genom Inst, Santa Cruz, CA USA
[9] Univ Calif Santa Cruz, Dept Mol Cell & Dev Biol, Santa Cruz, CA USA
关键词
D O I
暂无
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
B282/P1964
引用
收藏
页码:583 / 583
页数:1
相关论文
共 50 条
  • [41] TERT promoter mutations in melanoma render TERT expression dependent on MAPK pathway activation
    Vallarelli, Andrelou F.
    Rachakonda, P. Sivaramakrishna
    Andre, Jocelyne
    Heidenreich, Barbara
    Riffaud, Laurence
    Bensussan, Armand
    Kumar, Rajiv
    Dumaz, Nicolas
    ONCOTARGET, 2016, 7 (33) : 53127 - 53136
  • [42] TERT Promoter Mutations Increase Sense and Antisense Transcription from the TERT Promoter
    Hafezi, Francois
    Jaxel, Lisa
    Lemaire, Morgane
    Turner, Jonathan D.
    Perez-Bercoff, Danielle
    BIOMEDICINES, 2021, 9 (12)
  • [43] TERT promoter mutations and BRAF mutations are rare in sporadic, and TERT promoter mutations are absent in NF1-related malignant peripheral nerve sheath tumors
    Hendrikus J. Dubbink
    Hannah Bakels
    Edward Post
    Ellen C. Zwarthoff
    Robert M. Verdijk
    Journal of Neuro-Oncology, 2014, 120 : 267 - 272
  • [44] TERT promoter mutations and BRAF mutations are rare in sporadic, and TERT promoter mutations are absent in NF1-related malignant peripheral nerve sheath tumors
    Dubbink, Hendrikus J.
    Bakels, Hannah
    Post, Edward
    Zwarthoff, Ellen C.
    Verdijk, Robert M.
    JOURNAL OF NEURO-ONCOLOGY, 2014, 120 (02) : 267 - 272
  • [45] TERT promoter mutations and monoallelic activation of TERT in cancer
    F W Huang
    C M Bielski
    M L Rinne
    W C Hahn
    W R Sellers
    F Stegmeier
    L A Garraway
    G V Kryukov
    Oncogenesis, 2015, 4 : e176 - e176
  • [46] TERT promoter mutations and monoallelic activation of TERT in cancer
    Huang, F. W.
    Bielski, C. M.
    Rinne, M. L.
    Hahn, W. C.
    Sellers, W. R.
    Stegmeier, F.
    Garraway, L. A.
    Kryukov, G. V.
    ONCOGENESIS, 2015, 4 : e176 - e176
  • [47] Association between TERT promoter mutations and BRAF/NRAS mutations in patients with primary and metastatic melanoma tumors
    Chang, Gregory A.
    Tadepalli, Jyothirmayee S.
    Fleming, Nathaniel H.
    Lui, Kevin
    Shao, Yongzhao
    Darvishian, Farbod
    Pavlick, Anna
    Berman, Russell
    Shapiro, Richard
    Osman, Iman
    Polsky, David
    CANCER RESEARCH, 2015, 75
  • [48] Re: Mutations in TERT Promoter and FGFR3 and Telomere Length in Bladder Cancer
    Atala, Anthony
    JOURNAL OF UROLOGY, 2016, 195 (04): : 1168 - +
  • [49] TERT promoter mutations and telomerase expression in melanoma in adolescents and young adults.
    Seynnaeve, Brittani
    Lee, Seungjae
    Park, Yongseok
    Pappo, Alberto S.
    Kirkwood, John M.
    Bahrami, Armita
    JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (15)
  • [50] Patterns of Telomerase reverse transcriptase (TERT) promoter mutations in melanoma and bladder cancer
    Kumar, Rajiv
    Heidenreich, Barbara
    Hosen, Ismail
    Rachakonda, Sivaramakrishna
    Hemminki, Kari
    CANCER RESEARCH, 2014, 74 (19)