Essential Oils: Chemistry and Pharmacological Activities

被引：104
|
作者：
de Sousa, Damiao P. [1 ]
Damasceno, Renan Oliveira S. [2 ]
Amorati, Riccardo [3 ]
Elshabrawy, Hatem A. [4 ]
de Castro, Ricardo D. [5 ]
Bezerra, Daniel P. [6 ]
Nunes, Vitoria Regina V. [1 ]
Gomes, Rebeca C. [1 ]
Lima, Tamires C. [7 ]
机构：
[1] Univ Fed Paraiba, Dept Pharmaceut Sci, BR-58051900 Joao Pessoa, Brazil
[2] Univ Fed Pernambuco, Dept Physiol & Pharmacol, Ctr Biosci, BR-50670901 Recife, Brazil
[3] Univ Bologna, Dept Chem G Ciamician, Via Gobetti 83, I-40129 Bologna, Italy
[4] Sam Houston State Univ, Coll Osteopath Med, Dept Mol & Cellular Biol, Conroe, TX 77304 USA
[5] Univ Fed Paraiba, Dept Clin & Social Dent, BR-58051970 Joao Pessoa, Brazil
[6] Fundacao Oswaldo Cruz IGM FIOCRUZ BA, Inst Goncalo Moniz, BR-40296710 Salvador, Brazil
[7] Univ Fed Sergipe, Dept Pharm, BR-49100000 Sao Cristovao, Brazil
来源：
BIOMOLECULES | 2023年 / 13卷 / 07期
关键词：
natural products; metabolites; medicinal plants; volatiles; anti-inflammatory; antioxidant; antiviral; anticancer; antibacterial; antifungal; HERPES-SIMPLEX-VIRUS; INDUCED INTESTINAL MUCOSITIS; OREGANO ESSENTIAL OIL; IN-VITRO; ANTIVIRAL ACTIVITY; ANTIMICROBIAL ACTIVITY; GAMMA-TERPINENE; AROMATIC PLANTS; CARVACROL; 5-ISOPROPYL-2-METHYLPHENOL; ANTIINFLAMMATORY ACTIVITY;
D O I：
10.3390/biom13071144
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In this review, we provide an overview of the current understanding of the main mechanisms of pharmacological action of essential oils and their components in various biological systems. A brief introduction on essential oil chemistry is presented to better understand the relationship of chemical aspects with the bioactivity of these products. Next, the antioxidant, anti-inflammatory, antitumor, and antimicrobial activities are discussed. The mechanisms of action against various types of viruses are also addressed. The data show that the multiplicity of pharmacological properties of essential oils occurs due to the chemical diversity in their composition and their ability to interfere with biological processes at cellular and multicellular levels via interaction with various biological targets. Therefore, these natural products can be a promising source for the development of new drugs.
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页数：29
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