THE EFFECT OF MAVACAMTEN TREATMENT FOR SYMPTOMATIC, OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY IN PATIENTS OF OLDER AGE AND LONGER DURATION OF DIAGNOSIS: ANALYSIS OF THE EXPLORER-HCM TRIAL

被引：0
|
作者：
Wang, Andrew [1 ]
Lakdawala, Neal K. [1 ]
Abraham, Theodore P. [1 ]
Nilles, Ester Kim [1 ]
Wojdyla, Daniel M. [1 ]
Owens, Anjali Tiku [1 ]
Bach, Richard G. [1 ]
Saberi, Sara [1 ]
Sehnert, Amy [1 ]
Cresci, Sharon [1 ]
机构：
[1] Duke Univ, Durham, NC USA
来源：
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | 2023年 / 81卷 / 08期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
1042-13
引用
收藏
页码：327 / 327
页数：1
相关论文
共 50 条
  • [41] Serial changes in left and right ventricular global longitudinal strain in symptomatic obstructive hypertrophic cardiomyopathy treated with mavacamten: insights from VALOR-HCM trial
    Desai, M.
    Okushi, Y.
    Popovic, Z.
    Wolski, K.
    Owens, A.
    Geske, J.
    Saberi, S.
    Wang, A.
    Cremer, P.
    Tower-Rader, A.
    Lakdawala, N.
    Fermin, D.
    Naidu, S.
    Lampl, K.
    Sehnert, A.
    EUROPEAN HEART JOURNAL, 2024, 45
  • [42] Mavacamten Treatment in Patients With Obstructive and Nonobstructive Hypertrophic Cardiomyopathy: A Pooled Safety Analysis of 5 Clinical Trials
    Fermin, David
    Saberi, Sara
    Abraham, Theodore P.
    Olivotto, Iacopo
    Masri, Ahmad
    Sehnert, Amy J.
    Minton, Neil
    Fox, Shawna
    Bach, Richard G.
    CIRCULATION, 2022, 146
  • [43] LONG-TERM SAFETY AND EFFICACY OF MAVACAMTEN IN PATIENTS (PTS) WITH SYMPTOMATIC OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY (HCM): UPDATED RESULTS FROM THE PIONEER-OLE STUDY
    Masri, Ahmad
    Lester, Steven J.
    Stendahl, John
    Hegde, Sheila M.
    Sehnert, Amy
    Balaratnam, Ganesh
    Fox, Shawna
    Wang, Andrew
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2023, 81 (08) : 346 - 346
  • [44] Efficacy of Mavacamten in Patients with Symptomatic Hypertrophic Cardiomyopathy: Sub-Group Analyses by Background Beta-Blocker Use from the EXPLORER- HCM and MAVA-LTE Studies
    Jacoby, Daniel L.
    Wheeler, Matthew T.
    Elliott, Perry M.
    Saberi, Sara
    Sehnert, Amy J.
    Edelberg, Jay M.
    Li, Wanying
    Olivotto, Iacopo
    CIRCULATION, 2021, 144
  • [45] Design of DISCOVER-HCM: A Registry of Real-world Treatment Patterns and Outcomes of Patients with Symptomatic Obstructive Hypertrophic Cardiomyopathy
    Hernandez, Adrian
    Masoudi, Frederick
    Mazimba, Sula
    Saberi, Sara
    Setoguchi, Soko
    Spertus, John
    Shen, Sophie
    Balaratnam, Ganesh
    Chen, Yu-Mao
    Afsari, Sonia
    Minton, Neil
    Januzzi, James
    JOURNAL OF CARDIAC FAILURE, 2024, 30 : S4 - S4
  • [46] Long-term effects of mavacamten treatment in obstructive hypertrophic cardiomyopathy (HCM): updated cumulative analysis of the EXPLORER cohort of MAVA-long-term extension (LTE) study up to 120 weeks
    Garcia-Pavia, P.
    Oreziak, A.
    Masri, A.
    Barriales-Villa, R.
    Abraham, T. P.
    Owens, A. T.
    Lakdawala, N. K.
    Saberi, S.
    Wang, A.
    Wheeler, M. T.
    Choudhury, L.
    Balaratnam, G.
    Fox, S.
    Hegde, S. M.
    Olivotto, I.
    EUROPEAN HEART JOURNAL, 2023, 44
  • [47] Effect of Mavacamten on Systolic Anterior Motion of the Mitral Valve and Mitral Regurgitation in Patients With Obstructive Hypertrophic Cardiomyopathy: Insights From the VALOR-HCM Study
    Cremer, Paul C.
    Geske, Jeffrey B.
    Owens, Anjali T.
    Jaber, Wael A.
    Harb, Serge C.
    Saberi, Sara
    Wang, Andrew
    Naidu, Srihari S.
    Schaff, Hartzell V.
    Smedira, Nicholas G.
    Wang, Quing
    Lampl, Kathy
    Sehnert, Amy J.
    Nissen, Steven E.
    Desai, Milind Y.
    CIRCULATION, 2022, 146
  • [48] 96-WEEK CARDIAC MAGNETIC RESONANCE (CMR) RESULTS OF TREATMENT WITH MAVACAMTEN FROM THE EXPLORER COHORT OF THE MAVA-LONG-TERM EXTENSION (LTE) STUDY IN PATIENTS (PTS) WITH OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY (HCM)
    Saberi, Sara
    Kramer, Christopher M.
    Oreziak, Artur
    Masri, Ahmad
    Villa, Roberto Barriales
    Abraham, Theodore P.
    Lakdawala, Neal K.
    Wang, Andrew
    Choudhury, Lubna
    Rader, Florian
    Hegde, Sheila M.
    Kwong, Raymond Y.
    Balaratnam, Ganesh
    Kurio, Greg
    Fox, Shawna
    Olivotto, Iacopo
    Owens, Anjali Tiku
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2023, 81 (08) : 326 - 326
  • [49] INCREASE IN HCM-RELATED ECONOMIC BURDEN DUE TO ATRIAL FIBRILLATION IN PATIENTS WITH SYMPTOMATIC OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY: A CLAIMS ANALYSIS OF 9490 PATIENTS
    Butzner, M.
    Papademetriou, E.
    Potluri, R.
    Liu, X.
    Shreay, S.
    VALUE IN HEALTH, 2023, 26 (12) : S172 - S172
  • [50] Changes in standard of care (SOC) medication during long-term mavacamten treatment for obstructive hypertrophic cardiomyopathy (HCM): results from the EXPLORER cohort of MAVA-Long-Term Extension (LTE)
    Lakdawala, N.
    Afshar, K.
    Barriales-Villa, R.
    Gimeno-Blanes, J.
    Michels, M.
    Saberi, S.
    Wheeler, M. T.
    Balaratnam, G.
    Shah, A.
    Chen, Y. M.
    Sehnert, A. J.
    Abraham, T. P.
    EUROPEAN HEART JOURNAL, 2023, 44
12345