A diffusion barrier limits nuclear leaks

被引:0
|
作者
Shah, Hiral [1 ]
Dey, Gautam [1 ]
机构
[1] European Mol Biol Lab EMBL, Cell Biol & Biophys, Heidelberg, Germany
关键词
D O I
10.1038/s41556-023-01243-4
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
ESCRT-III seals holes in the nuclear envelope (NE). A study now shows that the Cmp7-directed ESCRT-III cascade that grommets and reseals NE holes after spindle pole body (SPB) extrusion at the end of fission yeast mitosis is complemented by the presence of a proteinaceous diffusion barrier to ensure NE integrity.
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页码:1411 / 1412
页数:2
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