T cell engager (TCE) score in patients treated with bispecific CD3 TCE in phase I clinical trials

被引：0
|
作者：
Herbel, Noe
Goldschmidt, Vincent
Michot, Jean-Marie
Laparra, Ariane
Geraud, Arthur
Ouali, Kaissa
Danlos, Francois-Xavier
Vuagnat, Perrine
Bernard-Tessier, Alice
Gazzah, Anas
Bahleda, Rastilav
Hollebecque, Antoine
Marabelle, Aurelien
Postel-Vinay, Sophie
Loriot, Yohann
Massard, Christophe
Ribrag, Vincent
Aix, Santiago Ponce
Champiat, Stephane
Baldini, Capucine
机构：
[1] Gustave Roussy, Drug Dev Dept DITEP, Villejuif, France
[2] Gustave Roussy, Dept Interdisciplinaire Org Parcours Patient DIOP, Villejuif, France
[3] Gustave Roussy Inst, Med Oncol Dept, Villejuif, France
[4] Gustave Roussy, Drug Dev Dept, Canc Campus, Villejuif, France
[5] Gustave Roussy, Drug Dev Dept, Villejuif, France
来源：
JOURNAL OF CLINICAL ONCOLOGY | 2023年 / 41卷 / 16期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
2573
引用
收藏
页数：1
相关论文
共 50 条
  • [31] Phase I Trial of DLL3/CD3 IgG-Like T-Cell Engager BI 764532 in Patients with DLL3-Positive Tumors: Patients with LCNEC
    Wermke, M.
    Gambardella, V.
    Kuboki, Y.
    Alese, O. B.
    Morgensztern, D.
    Sayehli, C.
    Sanmamed, M. F.
    Arriola, E.
    Wolf, J.
    Villaruz, L.
    Studeny, M.
    Bouzaggou, M.
    Fang, X.
    Felip, E.
    JOURNAL OF THORACIC ONCOLOGY, 2024, 19 (10) : S32 - S32
  • [32] A multicenter phase 1 study of solitomab (MT110, AMG 110), a bispecific EpCAM/CD3 T-cell engager (BiTE®) antibody construct, in patients with refractory solid tumors
    Kebenko, Maxim
    Goebeler, Marie-Elisabeth
    Wolf, Martin
    Hasenburg, Annette
    Seggewiss-Bernhardt, Ruth
    Ritter, Barbara
    Rautenberg, Beate
    Atanackovic, Djordje
    Kratzer, Andrea
    Rottman, James B.
    Friedrich, Matthias
    Vieser, Eva
    Elm, Stefanie
    Patzak, Ingrid
    Wessiepe, Dorothea
    Stienen, Sabine
    Fiedler, Walter
    ONCOIMMUNOLOGY, 2018, 7 (08):
  • [33] A novel B7-H3 x CD3 bispecific T-cell engager for the treatment of B7-H3+ tumors
    Li, Feng
    Liu, Ming
    Hua, Yanan
    Wei, Xuemei
    Qin, Luying
    Cao, Guangcan
    Yang, Daniel Chunxu
    Zhang, Wenjun
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (16)
  • [34] Immunodepletion of MDSC By AMV564, a Novel Tetravalent Bispecific CD33/CD3 T Cell Engager Restores Immune Homeostasis in MDS in Vitro
    Cheng, Pingyan
    Eksioglu, Erika
    Chen, Xianghong
    Wei, Max
    Guenot, Jeanmarie
    Fox, Judy
    List, Alan F.
    Wei, Sheng
    BLOOD, 2017, 130
  • [35] ZW38, a Novel Azymetric Bispecific CD19-Directed CD3 T Cell Engager Antibody Drug Conjugate with Controlled T Cell Activation and Improved B Cell Cytotoxicity
    Ng, Gordon
    Spreter, Thomas
    Davies, Rupert
    Wickman, Grant
    BLOOD, 2016, 128 (22)
  • [36] Microenvironment-responsive anti-PD-L1 x CD3 bispecific T-cell engager for solid tumor immunotherapy
    Liu, Dingkang
    Bao, Lichen
    Zhu, Haichao
    Yue, Yali
    Tian, Jing
    Gao, Xiangdong
    Yin, Jun
    JOURNAL OF CONTROLLED RELEASE, 2023, 354 : 606 - 614
  • [37] Nonshrinkable Thermosensitive Hydrogels Combined with Bispecific Anti-PSMA/CD3 T-Cell Engager for Effective Against Tumors in Mice Model
    Wei, Pu-Sheng
    Chou, Po-Yu
    Hsu, Hao-Yi
    Chen, Michael
    Chen, Yi-Jou
    Tsai, Tung-Han
    Wen, Bang-Yu
    Sheu, Ming-Thau
    Chuang, Kuo-Hsiang
    Lin, Hong-Liang
    INTERNATIONAL JOURNAL OF NANOMEDICINE, 2025, 20 : 3083 - 3111
  • [38] Generation of a novel ROR1 x CD3 bispecific T-cell engager for better tumor killing and minimal cytokine release
    Wu, Danqing
    Gong, Shiyong
    Wu, Xuan
    Naren, Gaowa
    Dong, Liqin
    Lensky, Stephan
    Wu, Chengbin
    CANCER RESEARCH, 2024, 84 (07)
  • [39] Enhanced cytotoxicity in multiple myeloma via T cells armed with bispecific T cell engager targeting B-cell maturation antigen on cancer cells and CD3 on T cells
    Supimon, Kamonlapat
    Sangsuwannukul, Thanich
    Luangwattananun, Piriya
    Yenchitsomanus, Pa-thai
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 143
  • [40] A Novel Bispecific T-Cell Engager (CD1a x CD3ε) BTCE Is Effective against Cortical-Derived T Cell Acute Lymphoblastic Leukemia (T-ALL) Cells
    Riillo, Caterina
    Caracciolo, Daniele
    Grillone, Katia
    Polera, Nicoletta
    Tuccillo, Franca Maria
    Bonelli, Patrizia
    Juli, Giada
    Ascrizzi, Serena
    Scionti, Francesca
    Arbitrio, Mariamena
    Lopreiato, Mariangela
    Siciliano, Maria Anna
    Sestito, Simona
    Talarico, Gabriella
    Galea, Eulalia
    Galati, Maria Concetta
    Pensabene, Licia
    Loprete, Giovanni
    Rossi, Marco
    Ballerini, Andrea
    Gentile, Massimo
    Britti, Domenico
    Di Martino, Maria Teresa
    Tagliaferri, Pierosandro
    Tassone, Pierfrancesco
    CANCERS, 2022, 14 (12)
12345