Functional magnetic resonance imaging in coronavirus disease 2019 induced olfactory dysfunction

被引:1
|
作者
Iravani, Kamyar [1 ]
Malekpour, Behzad [1 ]
Rasekhi, Alireza [2 ]
Faramarzi, Ali [1 ,3 ]
Soltaniesmaeili, Amir [1 ]
Golkhar, Behnaz [1 ]
Jahanandish, Farimah [1 ]
Babaei, Amirhossein [1 ,3 ]
机构
[1] Shiraz Univ Med Sci, Otolaryngol Res Ctr, Dept Otolaryngol, Shiraz, Iran
[2] Shiraz Univ Med Sci, Med Imaging Res Ctr MIRC, Sch Med, Dept Radiol, Shiraz, Iran
[3] Shiraz Univ Med Sci, Student Res Comm, Shiraz, Iran
来源
JOURNAL OF LARYNGOLOGY AND OTOLOGY | 2024年 / 138卷 / 02期
关键词
Coronavirus; diagnostic imaging; magnetic resonance imaging; smell; quality of life; SMELL IDENTIFICATION TEST;
D O I
10.1017/S0022215123001652
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
ObjectiveTo evaluate the functional magnetic resonance imaging changes in the olfactory structures of coronavirus disease 2019 patients experiencing olfactory dysfunction.MethodsThis study included patients aged 25-65 years who presented with a sudden loss of smell, confirmed coronavirus disease 2019 infection, and persistent olfactory dysfunction for a minimum of 2 months without any treatment.ResultsIrrespective of the side of brain activation, the analysis of the cumulative maximum diameter of the activation zones revealed significantly lower activation in the upper frontal lobe (p = 0.037) and basal ganglia (p = 0.023) in olfactory dysfunction patients. Irrespective of the side of activation, the analysis of the number of activation points demonstrated significantly lower activation in the upper frontal lobe (p = 0.036) and basal ganglia (p = 0.009) in olfactory dysfunction patients.ConclusionPatients with coronavirus-triggered olfactory dysfunction exhibited lower activity in their basal ganglia and upper frontal lobe.
引用
收藏
页码:178 / 183
页数:6
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