Ameliorating Effects of Virgin Coconut Oil (VCO) on Nicotine Dependence and Quality of Life in Smokers

被引:0
|
作者
Anggadiredja, Kusnandar [1 ]
Amalia, Lia [1 ]
Haq, Fahmy Ahsanul [1 ]
机构
[1] Bandung Inst Technol, Sch Pharm, Dept Pharmacol & Clin Pharm, Bandung, Indonesia
关键词
Virgin coconut oil; nicotine dependence; fagerstrom test for nicotine dependence; quality of life; smokers; CANNABINOID WITHDRAWAL; OPIATE WITHDRAWAL; NORADRENALINE; ABSTINENCE; EXPRESSION; PREVENTS; RELEASE; RELAPSE;
D O I
10.2174/1871527322666221128141647
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Background Safer and effective alternatives to manage nicotine dependence are still required. Preliminary studies have shown the potential of virgin coconut oil (VCO) to be used in dependence treatment. Objective To assess the VCO effect administered for 14 days on nicotine dependence and quality of life. Methods Forty smoking subjects participated in an open-label, single-center, pre/post-intervention study, and were required to take 15 ml VCO twice daily for 14 days. They were evaluated with the Fagerstrom Test for Nicotine Dependence (FTND) for nicotine dependence intensity and EuroQolvisual analogue scales (EQ VAS) for quality of life. Results The VCO regimen improved FTND (0.53 points decrease, p<0.05) and EQ-VAS (5.85 points increase p<0.01) scores. Adverse events were all mild. Conclusion Results of the present study suggest that VCO has the potential to be a safe and effective adjunct therapy for the management of nicotine dependence.
引用
收藏
页码:1243 / 1249
页数:7
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