Potential biomarkers in endometrial cancer: a narrative review

被引:8
|
作者
Moar, Kareena [1 ]
Pant, Anuja [1 ]
Saini, Vikas [2 ]
Maurya, Pawan Kumar [1 ]
机构
[1] Cent Univ Haryana, Dept Biochem, Mahendragarh 123031, India
[2] Cent Univ Haryana, Dept Vocat Studies & Skill Dev, Biomed Sci, Mahendragarh, India
关键词
Endometrial cancer; biomarker; mutation; classification; angiogenic factors; MISMATCH REPAIR-DEFICIENCY; POLYCYSTIC-OVARY-SYNDROME; ORAL-CONTRACEPTIVES; BREAST-CANCER; IMMUNOHISTOCHEMICAL EXPRESSION; RECEPTOR-ALPHA; LYNCH SYNDROME; CARCINOMA; RISK; ESTROGEN;
D O I
10.1080/1354750X.2023.2179114
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
ContextEvery year, approximately 0.4 million women suffer from endometrial cancer (EC) worldwide and it has become the most common gynecological malignancy. Almost 66% of EC cases are diagnosed at an early stage and can be cured by performing surgery while those at an advanced stage turns out to be fatal. Biomarkers of endometrial cancer would be very valuable for screening of women who are at high risk and in detecting the chance of recurrence of disease.ObjectiveThe current article has reviewed studies published on expression of biomarkers and susceptibility to EC.MethodsGoogle Scholar and PubMed were used as searching platforms and we have majorly considered the literature from last 10 years.ResultsPotential biomarkers of EC identified from various studies were summarised.
引用
收藏
页码:358 / 371
页数:14
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