Characterization of carbapenem-resistant Escherichia coli and Klebsiella: a role for AmpC-producing isolates

被引：1
|
作者：
Rizi, Kobra S. [1 ,2 ]
Aryan, Ehsan [2 ]
Youssefi, Masoud [2 ]
Ghazvini, Kiarash [2 ]
Meshkat, Zahra [2 ]
Amini, Yousef [3 ]
Safdari, Hadi [2 ]
Derakhshan, Mohammad [2 ]
Farsiani, Hadi [2 ]
机构：
[1] Mashhad Univ Med Sci, Sch Med, Dept Microbiol & Virol, Mashhad, Iran
[2] Mashhad Univ Med Sci, Antimicrobial Resistance Res Ctr, Mashhad, Iran
[3] Zahedan Univ Med Sci, Resistant TB Inst, Infect Dis & Trop Med Res Ctr, Zahedan, Iran
来源：
FUTURE MICROBIOLOGY | 2023年
关键词：
AmpC beta-lactamases; antimicrobial resistance; carbapenemase-coding genes; Enterobacterales; extended-spectrum beta-lactamase enzymes; SPECTRUM-BETA-LACTAMASE; HIGH PREVALENCE; ENTEROBACTERIACEAE; PNEUMONIAE; PSEUDOMONAS; MECHANISMS; COMMUNITY; BACTERIA; GENES;
D O I：
10.2217/fmb-2021-0211
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Aim: This study aimed to investigate the role of AmpC enzymes in carbapenem resistance among AmpC/extended-spectrum ss-lactamase (ESBL)-producing clinical isolates of Escherichia coli and Klebsiella spp. Methods: Fifty-six bacterial strains that were AmpC producers were examined. The antibiotic susceptibility test was performed by the disk diffusion and E-test. The prevalence of the plasmid carbapenemase was determined using PCR. Results: The resistance to meropenem in the AmpC(+)/ESBL+ group was 64%, higher than that reported for the AmpC(-)/ESBL+ group. Ten isolates of the carbapenemresistant AmpC producers were negative for carbapenemase-encoding genes. Conclusion: Carbapenem resistance among AmpC-producing isolates with negative results for carbapenemase-encoding genes potentially demonstrates the role of AmpC enzymes among these isolates.
引用
收藏
页码：215 / 223
页数：9
相关论文
共 50 条
  • [31] Molecular characterization of carbapenem-resistant Klebsiella pneumoniae isolates from a university hospital in Brazil
    Polano Vivan, Ana Carolina
    Rosa, Juliana Ferraz
    Rizek, Camila Fonseca
    Pelisson, Marsileni
    Costa, Silvia Figueiredo
    Hungria, Mariangela
    Takayama Kobayashi, Renata Katsuko
    Vespero, Eliana Carolina
    JOURNAL OF INFECTION IN DEVELOPING COUNTRIES, 2017, 11 (05): : 379 - 386
  • [32] High prevalence of multidrug resistant ESBL- and plasmid mediated AmpC-producing clinical isolates of Escherichia coli at Maputo Central Hospital, Mozambique
    Estaleva, Calvina E. L.
    Zimba, Tomas F.
    Sekyere, John Osei
    Govinden, Usha
    Chenia, Hafizah Y.
    Simonsen, Gunnar S.
    Haldorsen, Bjorg
    Essack, Sabiha Y.
    Sundsfjord, Arnfinn
    BMC INFECTIOUS DISEASES, 2021, 21 (01)
  • [33] High prevalence of multidrug resistant ESBL- and plasmid mediated AmpC-producing clinical isolates of Escherichia coli at Maputo Central Hospital, Mozambique
    Calvina E. L. Estaleva
    Tomas F. Zimba
    John Osei Sekyere
    Usha Govinden
    Hafizah Y. Chenia
    Gunnar S. Simonsen
    Bjørg Haldorsen
    Sabiha Y. Essack
    Arnfinn Sundsfjord
    BMC Infectious Diseases, 21
  • [34] Spread of ESBL/AmpC-producing Escherichia coli and Klebsiella pneumoniae in the community through ready-to-eat sandwiches in Algeria
    Yaici, Lydia
    Haenni, Marisa
    Metayer, Veronique
    Saras, Estelle
    Zekar, Ferielle Mesbah
    Ayad, Meriem
    Touati, Abdelaziz
    Madec, Jean-Yves
    INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 2017, 245 : 66 - 72
  • [35] ESBL/AmpC-Producing Escherichia coli in Wild Boar: Epidemiology and Risk Factors
    Formenti, Nicoletta
    Calo, Stefania
    Parisio, Giovanni
    Guarneri, Flavia
    Birbes, Laura
    Pitozzi, Alessandra
    Scali, Federico
    Tonni, Matteo
    Guadagno, Federica
    Giovannini, Stefano
    Salogni, Cristian
    Ianieri, Adriana
    Bellini, Silvia
    Pasquali, Paolo
    Alborali, Giovanni Loris
    ANIMALS, 2021, 11 (07):
  • [36] Characterization of ESBL/AmpC-producing extraintestinal Escherichia coli (ExPEC) in dogs treated at a veterinary hospital in Brazil
    Silva, Brendhal Almeida
    Amarante, Victor Santos do
    Xavier, Rafael Gariglio Clark
    Colombo, Salene Angelini
    Silva, Tales Fernando da
    Brenig, Bertram
    Aburjaile, Flavia Figueira
    Azevedo, Vasco Ariston de Carvalho
    Silva, Rodrigo Otavio Silveira
    RESEARCH IN VETERINARY SCIENCE, 2024, 166
  • [37] Molecular Characterization of Carbapenem resistant Escherichia coli and Klebsiella pneumoniae in Erbil, Iraq
    Ahmed, Heshu J.
    Ibrahim, Ahmad H.
    Al-Rawi, Sawsan S.
    Ganjo, Aryan R.
    Saber, Hataw Fryad
    JOURNAL OF POPULATION THERAPEUTICS AND CLINICAL PHARMACOLOGY, 2023, 30 (04): : E457 - E463
  • [38] ESBL- and AmpC-producing Escherichia coli from legally and illegally imported meat: Characterization of isolates brought into the EU from third countries
    Mueller, Anja
    Jansen, Wiebke
    Grabowski, Nils Th.
    Monecke, Stefan
    Ehricht, Ralf
    Kehrenberg, Corinna
    INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 2018, 283 : 52 - 58
  • [39] Investigation of Carbapenemases in Carbapenem-Resistant Escherichia coli and Klebsiella pneumoniae Strains Isolated in 2014 in Turkey
    Cakar, Asli
    Akyon, Yakut
    Gur, Deniz
    Karatuna, Onur
    Ogunc, Dilara
    Baysan, Betil Ozhak
    Coplu, Nilay
    Cagatay, Mustafa
    Kilic, Abdullah
    Baysallar, Mehmet
    Bakici, Zahir
    Celik, Cem
    Gulay, Zeynep
    Aydemir, Sohret
    Tunger, Alper
    Kilic, Huseyin
    Ercal, Baris Derya
    Toraman, Zulal Asci
    Zer, Yasemin
    Buyuktas, Ayse
    Ay, Selma
    Aktas, Zerrin
    Kayacan, Cigdem
    Bayramoglu, Gulcin
    Aydin, Faruk
    Dundar, Devrim
    Hasdemir, Ufuk
    Ayas, Ramazan
    Yanik, Keramettin
    Gunaydin, Murat
    Guducuoglu, Huseyin
    Parlak, Mehmet
    MIKROBIYOLOJI BULTENI, 2016, 50 (01): : 21 - 33
  • [40] Disc methods for detecting AmpC β-lactamase-producing clinical isolates of Escherichia coli and Klebsiella pneumoniae
    Brenwald, NP
    Jevons, G
    Andrews, J
    Ang, L
    Fraise, AP
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2005, 56 (03) : 600 - 601
12345