(Very) Small Stem-like Cells in Human Cell Cultures

被引：1

作者：

Lica, Jan Jakub ^{[1
,2
]}

Pradhan, Bhaskar ^{[3
]}

机构：

[1] Med Univ Warsaw, Fac Med, Dept Regenerat Med, PL-02097 Warsaw, Poland

[2] Univ Gdansk, Fac Chem, Dept Mol Biochem, PL-80308 Gdansk, Poland

[3] Med Univ Warsaw, Fac Pharm, Dept Biochem, PL-02097 Warsaw, Poland

来源：

CANCERS | 2023年 / 15卷 / 23期

关键词：

cell cultures: A549; HEK293; HL-60; Jurkat; KG1a; K562; and Raji; cancer stem-like cells; leukemic stem-like cells; very small cancer stem-like cells; very small leukemic stem-like cells; very small embryonic-like stem cells; cluster of differentiation: CD34; CD45; CD56; and CD2; CANCER; CD56;

D O I：

10.3390/cancers15235520

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Very Small Embryonic-like Stem Cells (VSELSCs) and Very Small Cancer Stem Cells (VSCSCs) are fields of intensive research. Although the presence in vitro of VSELSC and VSCSC cellular stage analogs appear probable, it has yet to be published. Utilizing established human cell cultures with varying populations of primitive cells, stained with CD markers specific to primitive stages, in addition to a fluorescent DNA dye, and following histochemical processing, we have developed a cytological method for detecting Very Small Leukemic Stem-like Cells (VSLSLCs), Very Small Cancer Stem-like Cells (VSCSLCs), and VSELSCs. This detection provides an opportunity to advance research in these areas.

引用

页数：12

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