Assessing vaginal wall thickness by transvaginal ultrasound in breast cancer survivors: A pilot study

被引:5
|
作者
Ros, Cristina [1 ]
Mension, Eduard [1 ,2 ]
Rius, Mariona [1 ]
Munmany, Meritxell [1 ]
De Guirior, Cristian [1 ]
Espuna-Pons, Montserrat [1 ]
Angles-Acedo, Sonia [1 ]
Castelo-Branco, Camil [1 ]
机构
[1] Univ Barcelona, Hosp Clin, Clin Inst Gynecol Obstet & Neonatol, Inst Invest Biomed August Pi i Sunyer IDIBAPS, Barcelona, Spain
[2] Hosp Clin Barcelona, Clin Inst Gynecol Obstet & Neonatol, Villarroel 170, Barcelona 8036, Spain
关键词
Vulvovaginal atrophy; Genitourinary syndrome of menopause; Vaginal ultrasound; Vaginal wall thickness; Pilot study; Breast cancer survivors; GENITOURINARY SYNDROME; POSTMENOPAUSAL WOMEN; SKIN COLLAGEN; MENOPAUSE; SYMPTOMS; THERAPY; ATROPHY; LASER;
D O I
10.1016/j.maturitas.2023.02.001
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Aim: There is need for a straightforward objective measure to evaluate vaginal wall changes related to hypo-estrogenism. The aim of this pilot study was to evaluate a transvaginal ultrasound procedure for the quantifi-cation of vaginal wall thickness in order to differentiate between healthy premenopausal women and postmenopausal women with genitourinary syndrome of menopause using ultra-low-level estrogen status as a model. Methods: We performed a prospective, two-arm, cross-sectional pilot study comparing vaginal wall thickness measured by transvaginal ultrasound in postmenopausal breast cancer survivors using aromatase inhibitors with genitourinary syndrome of menopause (GSM group) and healthy premenopausal women (control or C group) from October 2020 to March 2022. After intravaginal introduction of 20 cm3 of sonographic gel, vaginal wall thickness was measured by trans -vaginal ultrasound in the anterior, posterior, and right and left lateral walls (four quadrants). The study methods followed the STROBE checklist.Results: According to the results of a two-sided t-test, the mean vaginal wall thickness of the four quadrants in the GSM group was significantly less than that of the C group (2.25 mm vs 4.17 mm, respectively; p < 0.001). Likewise, the thickness of each of the vaginal walls (anterior, posterior, right and left lateral) statistically differed between the two groups (p < 0.001).Conclusion: Transvaginal ultrasound with intravaginal gel may be a feasible objective technique to assess geni-tourinary syndrome of menopause, showing clear differences in vaginal wall thickness between breast cancer survivors using aromatase inhibitors and premenopausal women.Possible correlations with symptoms or treatment response should be assessed in future studies.
引用
收藏
页码:7 / 12
页数:6
相关论文
共 50 条
  • [41] INTERACTIVE WELLNESS: ASSESSING THE EFFECTS OF SOMATOSENSORY-INTERACTIVE EXERCISE AND SOCIAL ENGAGEMENT ON FATIGUE IN BREAST CANCER SURVIVORS: A PILOT STUDY
    Jiang, Qinghan
    ONCOLOGY NURSING FORUM, 2024, 51 (02)
  • [42] Experience with transvaginal hydrolaparoscopy (TVHL) in assessing adnexal masses before performing vaginal surgery: a pilot surgery
    Prasad, J. U.
    Ramandeep, K.
    Neema, S.
    Priyata, L.
    Ritambahara, A.
    BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2015, 122 : 127 - 127
  • [43] Bowenwork for symptom management of women breast cancer survivors with lymphedema: A pilot study
    Argenbright, Christine A.
    Taylor-Piliae, Ruth E.
    Loescher, Lois J.
    COMPLEMENTARY THERAPIES IN CLINICAL PRACTICE, 2016, 25 : 142 - 149
  • [44] Cortisol levels and responses to mammography screening in breast cancer survivors: A pilot study
    Porter, LS
    Mishel, M
    Neelon, V
    Belyea, M
    Pisano, E
    Soo, MS
    PSYCHOSOMATIC MEDICINE, 2003, 65 (05): : 842 - 848
  • [45] Pilot study to assess prolonged nightly fasting in breast cancer survivors (LONGFAST)
    O'Donnell, Elizabeth K.
    Shapiro, Yael N.
    Comander, Amy
    Isakoff, Steven J.
    Moy, Beverly
    Spring, Laura
    Wander, Seth
    Kuter, Irene
    Shin, Jennifer
    Younger, Jerry
    Specht, Michelle
    Kourniotis, Chryssanthi
    Sullivan, Carol
    Winters, Loren
    Horick, Nora
    Peppercorn, Jeffrey
    CANCER RESEARCH, 2022, 82 (04)
  • [46] Effects of Different Volumes of Combined Training in Breast Cancer Survivors: A Pilot Study
    Pinto, Stephanie
    Portella, Elisa
    Alberton, Cristine
    Pinheiro, Rochele
    David, Gabriela
    Lopez, Pedro
    Brizio, Maria Laura
    Schaun, Gustavo
    Umpierre, Daniel
    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 2019, 51 (06): : 427 - 427
  • [47] Effects of concurrent aerobic and strength training on breast cancer survivors: a pilot study
    De Luca, V.
    Minganti, C.
    Borrione, P.
    Grazioli, E.
    Cerulli, C.
    Guerra, E.
    Bonifacino, A.
    Parisi, A.
    PUBLIC HEALTH, 2016, 136 : 126 - 132
  • [48] Acupuncture for symptoms management in Korean breast cancer survivors: a prospective pilot study
    Kim, Tae-Hun
    Kang, Jung Won
    ACUPUNCTURE IN MEDICINE, 2019, 37 (03) : 164 - 174
  • [49] Pilot study to assess prolonged overnight fasting in breast cancer survivors (longfast)
    O'Donnell, Elizabeth
    Shapiro, Yael
    Comander, Amy
    Isakoff, Steven
    Moy, Beverly
    Spring, Laura
    Wander, Seth
    Kuter, Irene
    Shin, Jennifer
    Specht, Michelle
    Kournioti, Chryssanthi
    Hu, Bonnie
    Sullivan, Carol
    Winters, Loren
    Horick, Nora
    Peppercorn, Jeffrey
    BREAST CANCER RESEARCH AND TREATMENT, 2022, 193 (03) : 579 - 587
  • [50] Improved sleep after Qigong exercise in breast cancer survivors: A pilot study
    Liu, Wen
    Schaffer, Lauren
    Herrs, Natalie
    Chollet, Christine
    Taylor, Sarah
    ASIA-PACIFIC JOURNAL OF ONCOLOGY NURSING, 2015, 2 (04) : 232 - 239