mSphere of Influence: Targeting bacterial signaling and metabolism to overcome antimicrobial resistance

被引:0
|
作者
Zeden, Merve S. [1 ]
机构
[1] Univ Galway, Coll Sci & Engn, Sch Biol & Chem Sci, Galway, Ireland
基金
爱尔兰科学基金会;
关键词
bacterial signalling; Staphylococcus aureus; Listeria monocytogenes; AMR; MRSA; ESKAPE; central metabolism; antibiotic resistance; beta-lactams; c-di-AMP; C-DI-AMP; BETA-LACTAM RESISTANCE; STAPHYLOCOCCUS-AUREUS; ANTIBIOTIC-RESISTANCE; CELL-WALL; STRESS-RESPONSE; GROWTH; SUSCEPTIBILITY; VANCOMYCIN; TOLERANCE;
D O I
10.1128/msphere.00632-23
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Dr Merve Suzan Zeden works in the field of molecular bacteriology and antibiotic resistance. In this mSphere of Influence article, she reflects on how three papers, entitled "c-di-AMP modulates Listeria monocytogenes central metabolism to regulate growth, antibiotic resistance and osmoregulation," "Amino acid catabolism in Staphylococcus aureus and the function of carbon catabolite repression," and "Evolving MRSA: high-level beta-lactam resistance in Staphylococcus aureus is associated with RNA polymerase alterations and fine tuning of gene expression," made an impact on her work on bacterial metabolism and antimicrobial resistance and how it shaped her research in understanding the link in between.
引用
收藏
页数:5
相关论文
共 50 条
  • [41] mSphere of Influence: the Importance of Metabolism for Pathogen Adaptation to Host-Imposed Stresses
    Amich, Jorge
    MSPHERE, 2019, 4 (04):
  • [42] Targeting epigenetic mechanisms to overcome venetoclax resistance
    Prado, Gabriel
    Kaestner, Charlotte L.
    Licht, Jonathan D.
    Bennett, Richard L.
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2021, 1868 (08):
  • [43] Epigenetic Targeting Therapies to Overcome Chemotherapy Resistance
    Balch, Curt
    Nephew, Kenneth P.
    EPIGENETIC ALTERATIONS IN ONCOGENESIS, 2013, 754 : 285 - 311
  • [44] Targeting CAFs to overcome anticancer therapeutic resistance
    Er Saw, Phei
    Chen, Jianing
    Song, Erwei
    TRENDS IN CANCER, 2022, 8 (07) : 527 - 555
  • [45] Bacterial resistance to silver nanoparticles and how to overcome it
    Panacek, Ales
    Kvitek, Libor
    Smekalova, Monika
    Vecerova, Renata
    Kolar, Milan
    Roderova, Magdalena
    Dycka, Filip
    Sebela, Marek
    Prucek, Robert
    Tomanec, Ondrej
    Zboril, Radek
    NATURE NANOTECHNOLOGY, 2018, 13 (01) : 65 - +
  • [46] β-lactamase inhibitors:: Agents to overcome bacterial resistance
    Maiti, SN
    Phillips, OA
    Micetich, RG
    Livermore, DM
    CURRENT MEDICINAL CHEMISTRY, 1998, 5 (06) : 441 - 456
  • [47] Bacterial resistance to silver nanoparticles and how to overcome it
    Aleš Panáček
    Libor Kvítek
    Monika Smékalová
    Renata Večeřová
    Milan Kolář
    Magdalena Röderová
    Filip Dyčka
    Marek Šebela
    Robert Prucek
    Ondřej Tomanec
    Radek Zbořil
    Nature Nanotechnology, 2018, 13 : 65 - 71
  • [48] Antimicrobial peptides targeting bacterial ribosome
    Lomakin, Ivan B.
    Gagnon, Matthieu G.
    Steitz, Thomas A.
    ONCOTARGET, 2015, 6 (22) : 18744 - 18745
  • [49] New approaches and agents to overcome bacterial resistance
    Domagala, JM
    Sanchez, JP
    ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 32, 1997, 32 : 111 - 120
  • [50] The hunt is on for new ways to overcome bacterial resistance
    Knudson, M
    TECHNOLOGY REVIEW, 1998, 100 (09): : 22 - 29