Autoimmune Polyendocrine Syndromes in the Pediatric Age

被引：7

作者：

Paparella, Roberto ^{[1
]}

Menghi, Michela ^{[1
]}

Micangeli, Ginevra ^{[1
]}

Leonardi, Lucia ^{[1
]}

Profeta, Giovanni ^{[1
]}

Tarani, Francesca ^{[2
]}

Petrella, Carla ^{[3
]}

Ferraguti, Giampiero ^{[2
]}

Fiore, Marco ^{[3
]}

Tarani, Luigi ^{[1
]}

机构：

[1] Sapienza Univ Rome, Dept Maternal Infantile & Urol Sci, Viale Policlin 155, I-00161 Rome, Italy

[2] Sapienza Univ Rome, Dept Expt Med, Viale Policlin 155, I-00161 Rome, Italy

[3] Inst Biochem & Cell Biol, IBBC CNR, I-00185 Rome, Italy

来源：

CHILDREN-BASEL | 2023年 / 10卷 / 03期

关键词：

autoimmune; polyendocrinopathy; polyglandular; immunodeficiency; pediatrics; children; autoantibodies; QUALITY-OF-LIFE; POLYGLANDULAR SYNDROME; ADRENAL INSUFFICIENCY; ADDISONS-DISEASE; CANDIDIASIS; MANIFESTATIONS; AUTOANTIBODIES; COMPLICATIONS; ENTEROPATHY; MANAGEMENT;

D O I：

10.3390/children10030588

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Autoimmune polyendocrine syndromes (APSs) encompass a heterogeneous group of rare diseases characterized by autoimmune activity against two or more endocrine or non-endocrine organs. Three types of APSs are reported, including both monogenic and multifactorial, heterogeneous disorders. The aim of this manuscript is to present the main clinical and epidemiological characteristics of APS-1, APS-2, and IPEX syndrome in the pediatric age, describing the mechanisms of autoimmunity and the currently available treatments for these rare conditions.

引用

页数：12

共 50 条

[21] Type 2 autoimmune polyendocrine syndromes (APS-2) DISCUSSION
Jaffiol, M. Claude
Charpentier, M. Bernard
Ardaillou, M. Raymond
Bouchard, M. Philippe
BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE, 2013, 197 (01): : 40 - 41
[22] Analysis of the AIRE Gene Promoter in Patients Affected by Autoimmune Polyendocrine Syndromes
Cudini, Annamaria
Nardella, Caterina
Bellacchio, Emanuele
Palma, Alessia
Delfino, Domenico Vittorio
Betterle, Corrado
Cappa, Marco
Fierabracci, Alessandra
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (05)
[23] Autoimmune adrenal insufficiency and autoimmune polyendocrine syndromes: Autoantibodies, autoantigens, and their applicability in diagnosis and disease prediction
Betterle, C
Dal Pra, C
Mantero, F
Zanchetta, R
ENDOCRINE REVIEWS, 2002, 23 (03) : 327 - 364
[24] Clinical characteristics of polyglandular autoimmune syndromes in pediatric age: an observational study
Bouca, Bruno
Nogueira, Andreia
Caetano, Joana
Cardoso, Rita
Dinis, Isabel
Mirante, Alice
JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, 2022, 35 (04): : 477 - 480
[25] Polyendocrine syndromes in dogs
Strey, Sina
Mischke, Reinhard
Rieder, Johanna
TIERAERZTLICHE PRAXIS AUSGABE KLEINTIERE HEIMTIERE, 2023, 51 (05): : 313 - 325
[26] THE POLYENDOCRINE DEFICIENCY SYNDROMES
LORIAUX, DL
NEW ENGLAND JOURNAL OF MEDICINE, 1985, 312 (24): : 1568 - 1569
[27] Primary immunodeficiency with autoimmune polyendocrine and hemorrhagic syndromes. Surgical dental tactics
Dolgikh, M.
Sarkisyan, N.
Chereshnev, V
EUROPEAN JOURNAL OF IMMUNOLOGY, 2019, 49 : 1230 - 1230
[28] Autoimmune polyendocrine disorders
Kämpe, O
CLINICAL CHEMISTRY, 2001, 47 (06) : S31 - S31
[29] Primary Pulmonary Arterial Hypertension and Autoimmune Polyendocrine Syndrome in a Pediatric Patient
Mohammed H. Alghamdi
Michelle Steinraths
Constadina Panagiotopoulos
James E. Potts
George G. S. Sandor
Pediatric Cardiology, 2010, 31 : 872 - 874
[30] Primary Pulmonary Arterial Hypertension and Autoimmune Polyendocrine Syndrome in a Pediatric Patient
Alghamdi, Mohammed H.
Steinraths, Michelle
Panagiotopoulos, Constadina
Potts, James E.
Sandor, George G. S.
PEDIATRIC CARDIOLOGY, 2010, 31 (06) : 872 - 874

← 1 2 3 4 5 →