The Mechanisms of Polysaccharides from Tonic Chinese Herbal Medicine on the Enhancement Immune Function: A Review

被引:13
|
作者
Xie, Zhiyi [1 ,2 ,3 ]
Jiang, Ninghua [4 ]
Lin, Minqiu [2 ,3 ]
He, Xinglishang [2 ,3 ]
Li, Bo [2 ,3 ]
Dong, Yingjie [1 ,2 ,3 ]
Chen, Suhong [1 ,2 ,3 ]
Lv, Guiyuan [1 ]
机构
[1] Zhejiang Chinese Med Univ, Coll Pharmaceut Sci, Hangzhou 310053, Peoples R China
[2] Zhejiang Univ Technol, Collaborat Innovat Ctr Yangtze River Delta Reg Gre, Huzhou 313200, Peoples R China
[3] Zhejiang Prov Key Lab TCM Innovat R&D & Digital In, Huzhou 313200, Peoples R China
[4] Jiaxing Univ, Affiliated Hosp 2, Jiaxing 314000, Peoples R China
来源
MOLECULES | 2023年 / 28卷 / 21期
基金
中国国家自然科学基金;
关键词
traditional Chinese medicine; polysaccharides; autoimmunity; mechanisms of action; POLYGONATUM-SIBIRICUM POLYSACCHARIDE; CYCLOPHOSPHAMIDE-INDUCED IMMUNOSUPPRESSION; LYCIUM-BARBARUM POLYSACCHARIDES; ACTIVATES T-LYMPHOCYTES; NF-KAPPA-B; STRUCTURAL-CHARACTERIZATION; ASTRAGALUS-MEMBRANACEUS; IMMUNOSTIMULATORY ACTIVITY; IMMUNOMODULATING ACTIVITY; SIGNALING PATHWAY;
D O I
10.3390/molecules28217355
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Tonic Chinese herbal medicine is a type of traditional Chinese medicine, and its primary function is to restore the body's lost nutrients, improve activity levels, increase disease resistance, and alleviate physical exhaustion. The body's immunity can be strengthened by its polysaccharide components, which also have a potent immune-system-protecting effect. Several studies have demonstrated that tonic Chinese herbal medicine polysaccharides can improve the body's immune response to tumor cells, viruses, bacteria, and other harmful substances. However, the regulatory mechanisms by which various polysaccharides used in tonic Chinese herbal medicine enhance immune function vary. This study examines the regulatory effects of different tonic Chinese herbal medicine polysaccharides on immune organs, immune cells, and immune-related cytokines. It explores the immune response mechanism to understand the similarities and differences in the effects of tonic Chinese herbal medicine polysaccharides on immune function and to lay the foundation for the future development of tonic Chinese herbal medicine polysaccharide products.
引用
收藏
页数:24
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