A case of midbrain germinoma: A literature review for radiographic and clinical features

被引：0

作者：

Miyake, Yohei ^{[1
]}

Tateishi, Kensuke ^{[1
,2
,7
]}

Oshima, Akito ^{[1
]}

Hongo, Takeshi ^{[1
]}

Satomi, Kaishi ^{[3
]}

Ichimura, Koichi ^{[4
]}

Kato, Ayumi ^{[5
]}

Iwashita, Hiromichi ^{[6
]}

Utsunomiya, Daisuke ^{[5
]}

Yamamoto, Tetsuya ^{[1
]}

机构：

[1] Yokohama City Univ, Grad Sch Med, Dept Neurosurg, Yokohama, Japan

[2] Yokohama City Univ, Grad Sch Med Sci, Lab Biopharmaceut & Regenerat Sci, Yokohama, Japan

[3] Kyorin Univ, Dept Pathol, Sch Med, Tokyo, Japan

[4] Juntendo Univ, Deparment Brain Dis Translat Res, Fac Med, Tokyo, Japan

[5] Yokohama City Univ Med, Dept Radiol, Yokohama, Japan

[6] Yokohama City Univ Med, Dept Pathol, Yokohama, Japan

[7] Yokohama City Univ, Dept Neurosurg, 3-9 Fukuura, Kanazawa, Yokohama 2360004, Japan

来源：

NEURO-ONCOLOGY ADVANCES | 2023年 / 5卷 / 01期

关键词：

literature review; midbrain germinoma; molecular genetics; GERM-CELL TUMORS;

D O I：

10.1093/noajnl/vdad043

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Intracranial germinomas mainly occur in the neurohypophyseal trunk and pineal body but are less frequent in the basal ganglia. Other sites are rare and account for only 6% of primary lesions of germinomas. Among them midbrain germ cell tumors are extremely rare, with only 9 cases reported to date. Here, we present a case of germinoma of the midbrain that was diagnosed using histopathological and DNA methylation classifier analysis. Through a literature review, we summarized the clinical and radiographic characteristics of midbrain germinomas for diagnostic and therapeutic development. © The Author(s) 2023.

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页数：6

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