Evidence-Based Guideline for the management of osteoporosis in men

被引：21

作者：

Fuggle, Nicholas R. ^{[1
]}

Beaudart, Charlotte ^{[2
,3
]}

Bruyere, Olivier ^{[3
]}

Abrahamsen, Bo ^{[4
]}

Al-Daghri, Nasser ^{[5
]}

Burlet, Nansa ^{[3
,6
]}

Chandran, Manju ^{[7
]}

Rosa, Mario M. ^{[8
]}

Cortet, Bernard ^{[9
]}

Demonceau, Celine ^{[3
]}

Dere, Willard ^{[10
]}

Halbout, Philippe ^{[11
]}

Hiligsmann, Mickael ^{[12
]}

Kanis, John A. ^{[13
,14
]}

Kaufman, Jean-Marc ^{[15
]}

Kurth, Andreas ^{[16
]}

Lamy, Olivier ^{[17
]}

Laslop, Andrea ^{[18
]}

Maggi, Stefania ^{[19
]}

Matijevic, Radmila ^{[20
]}

Mccloskey, Eugene ^{[13
]}

Mobasheri, Ali ^{[21
]}

Prieto Yerro, Maria C. ^{[22
]}

Radermecker, Regis P. ^{[23
]}

Sabico, Shaun ^{[5
]}

Al-Saleh, Yousef ^{[4
,24
]}

Silverman, Stuart ^{[25
]}

Veronese, Nicola ^{[26
]}

Rizzoli, Rene ^{[27
]}

Cooper, Cyrus ^{[1
,28
,29
]}

Reginster, Jean-Yves ^{[3
,30
]}

Harvey, Nicholas C. ^{[1
,28
]}

机构：

[1] Univ Southampton, MRC Lifecourse Epidemiol Ctr, Southampton, England

[2] Univ Namur, Fac Med, Clin Pharmacol & Toxicol Res Unit, NARILIS, Namur, Belgium

[3] WHO, Collaborating Ctr Epidemiol Musculoskeletal Hlth &, Liege, Belgium

[4] Univ Southern Denmark, Inst Clin Res, Odense Patient Data Explorat Network, Odense, Denmark

[5] King Saud Univ, Coll Sci, Chair Biomarkers Chron Dis, Biochem Dept, Riyadh, Saudi Arabia

[6] European Soc Clin & Econ Aspects Osteoporosis Oste, Liege, Belgium

[7] Singapore Gen Hosp, DUKE NUS Med Sch, Dept Endocrinol, Osteoporosis & Bone Metab Unit, Singapore, Singapore

[8] Univ Lisbon, Lab Clin Pharmacol & Therapeut, Lisbon, Portugal

[9] Univ Lille, Dept Rheumatol, Lille, France

[10] Univ Utah, Sch Med, Dept Internal Med, Salt Lake City, UT USA

[11] Int Osteoporosis Fdn IOF, Nyon, Switzerland

[12] Maastricht Univ, CAPHRI Care & Publ Hlth Res Inst, Dept Hlth Serv Res, Maastricht, Netherlands

[13] Univ Sheffield, Sch Med, Ctr Metab Bone Dis, Sheffield, S Yorkshire, England

[14] Australian Catholic Univ, Mary MacKillop Inst Hlth Res, Melbourne, Vic, Australia

[15] Ghent Univ Hosp, Dept Endocrinol, Ghent, Belgium

[16] Community Clin Middle Rhine, Dept Orthopaed & Trauma Surg, Campus Kemperhof, Koblenz, Germany

[17] CHU Vaudois, Ctr Interdisciplinaire Malad Osseuses, Dept Appareil Locomoteur, Lausanne, Switzerland

[18] Fed Off Safety Hlth Care, Sci Off, Vienna, Austria

[19] CNR Aging Branch IN, Padua, Italy

[20] Univ Novi Sad, Fac Med, Clin Ctr Vojvodina, Clin Orthoped Surg & Traumatol, Novi Sad, Serbia

[21] Univ Oulu, Fac Med, Res Unit Med Imaging Phys & Technol, Oulu, Finland

[22] Agencia Espanola Medicamentos & Prod Sanitarios, Madrid, Spain

[23] Univ Liege, CHU Liege, Dept Med Diabet Nutr & Metab Disorders, Liege, Belgium

[24] Dr Mohammad Alfagih Hosp, Dept Endocrinol, Riyadh, Saudi Arabia

[25] Cedars Sinai Med Ctr, Dept Med, Div Rheumatol, Los Angeles, CA USA

[26] Univ Palermo, Dept Internal Med, Geriatr Sect, I-90128 Palermo, Italy

[27] Geneva Univ Hosp, Div Bone Dis, Fac Med, Geneva, Switzerland

[28] Univ Hosp Southampton NHS Fdn Trust Southampton, NIHR Southampton Biomed Res Ctr, Southampton, Hants, England

[29] Univ Oxford, NIHR Oxford Biomed Res Ctr, Oxford, England

[30] King Saud Univ, Coll Sci, Prot Res Chair, Dept Biochem, Riyadh, Saudi Arabia

来源：

NATURE REVIEWS RHEUMATOLOGY | 2024年 / 20卷 / 04期

关键词：

TRABECULAR BONE SCORE; FRACTURE RISK REDUCTION; COST-UTILITY ANALYSIS; HIP FRACTURE; OLDER MEN; POSTMENOPAUSAL WOMEN; PARATHYROID-HORMONE; ZOLEDRONIC ACID; MINERAL DENSITY; EUROPEAN-SOCIETY;

D O I：

10.1038/s41584-024-01094-9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Historically, osteoporosis has been viewed as a disease of women, with research, trials of interventions and guidelines predominantly focused as such. It is apparent, however, that this condition causes a substantial health burden in men also, and that its assessment and management must ultimately be addressed across both sexes. In this article, an international multidisciplinary working group of the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases presents GRADE-assessed recommendations for the diagnosis, monitoring and treatment of osteoporosis in men. The recommendations are based on a comprehensive review of the latest research related to diagnostic and screening approaches for osteoporosis and its associated high fracture risk in men, covering disease burden, appropriate interpretation of bone densitometry (including the use of a female reference database for densitometric diagnosis in men) and absolute fracture risk, thresholds for treatment, and interventions that can be used therapeutically and their health economic evaluation. Future work should specifically address the efficacy of anti-osteoporosis medications, including denosumab and bone-forming therapies. In this Evidence-Based Guideline article, an international multidisciplinary working group of the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases presents recommendations for the diagnosis, monitoring and treatment of osteoporosis in men.

引用

页码：241 / 251

页数：11

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