Economic Evaluation of anti-epileptic Medicines for Autistic Children with Epilepsy

被引：1

作者：

Tinelli, Michela M. ^{[1
]}

Roddy, Aine ^{[1
,7
]}

Knapp, Martin ^{[1
]}

Arango, Celso ^{[2
]}

Mendez, Maria Andreina ^{[2
]}

Cusack, James ^{[3
]}

Murphy, Declan ^{[4
]}

Canitano, Roberto ^{[5
]}

Oakley, Bethany ^{[4
]}

Quoidbach, Vinciane ^{[6
]}

机构：

[1] London Sch Econ & Polit Sci, Care Policy & Evaluat Ctr, London, England

[2] Univ Complutense, Hosp Gen Univ Gregorio Maranon, Inst Psychiat & Mental Hlth, Sch Med,Dept Child & Adolescent Psychiat,CIBERSAM,, Madrid, Spain

[3] Autistica, London, England

[4] Kings Coll London, London, England

[5] Azienda Osped Univ Senese, Azienda, Siena, Italy

[6] European Brain Council, Brussels, Belgium

[7] Atlantic Technol Univ, Sligo, Ireland

来源：

JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS | 2024年 / 54卷 / 07期

基金：

欧盟地平线“2020”;

关键词：

Autism; Epilepsy; Children; Cost-effectiveness; Healthcare expenditure; Family impacts; COST-EFFECTIVENESS; ACTIVE EPILEPSY; YOUNG-ADULTS; CARE COSTS; CHILDHOOD; HEALTH; CONSEQUENCES; EDUCATION; DISORDER; IMPACT;

D O I：

10.1007/s10803-023-05941-8

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

We examine the cost-effectiveness of treating epilepsy with anti-epileptic medicines in autistic children, looking at impacts on healthcare providers (in England, Ireland, Italy and Spain) and children's families (in Ireland). We find carbamazepine to be the most cost-effective drug to try first in children with newly diagnosed focal seizures. For England and Spain, oxcarbazepine is the most cost-effective treatment when taken as additional treatment for those children whose response to monotherapy is suboptimal. In Ireland and Italy, gabapentin is the most cost-effective option. Our additional scenario analysis presents the aggregate cost to families with autistic children who are being treated for epilepsy: this cost is considerably higher than healthcare provider expenditure.

引用

页码：2733 / 2741

页数：9

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