Application of Collagen-Based Hydrogel in Skin Wound Healing

被引：61
|
作者：
Zhang, Yuan [1 ]
Wang, Yong [1 ]
Li, Ying [1 ]
Yang, Yunpeng [1 ]
Jin, Mingyuan [1 ]
Lin, Xiaoying [1 ]
Zhuang, Zeming [1 ]
Guo, Kai [1 ]
Zhang, Tao [1 ]
Tan, Weiqiang [1 ]
机构：
[1] Zhejiang Univ, Sir Run Run Shaw Hosp, Dept Plast Surg, Sch Med, 3 East Qingchun Rd, Hangzhou 310016, Peoples R China
来源：
GELS | 2023年 / 9卷 / 03期
基金：
中国国家自然科学基金;
关键词：
biopolymers; wound healing; collagen; skin repair; hydrogels; CROSS-LINKED COLLAGEN; MECHANICAL-PROPERTIES; IN-VITRO; MATRIX; LINKING; SCAFFOLDS; NANOPARTICLES; TRANSGLUTAMINASE; FABRICATION; STRENGTH;
D O I：
10.3390/gels9030185
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
The repair of skin injury has always been a concern in the medical field. As a kind of biopolymer material with a special network structure and function, collagen-based hydrogel has been widely used in the field of skin injury repair. In this paper, the current research and application status of primal hydrogels in the field of skin repair in recent years are comprehensively reviewed. Starting from the structure and properties of collagen, the preparation, structural properties, and application of collagen-based hydrogels in skin injury repair are emphatically described. Meanwhile, the influences of collagen types, preparation methods, and crosslinking methods on the structural properties of hydrogels are emphatically discussed. The future and development of collagen-based hydrogels are prospected, which is expected to provide reference for the research and application of collagen-based hydrogels for skin repair in the future.
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页数：24
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