Use of mesoporous silicas as the carriers for anti-inflammatory steroid drugs

被引：1
|
作者：
Geszke-Moritz, Malgorzata [1 ]
Moritz, Michal [2 ]
机构：
[1] Pomorskiego Uniwersytetu Med Szczecinie, Wydziale Farm Biotechnol Med & Med Lab, Zakladu Farmakognozji Nat Srodkow Lecznic, Szczecin, Poland
[2] Pomorskiego Uniwersytetu Med Szczecinie, Wydziale Farm Biotechnol Med & Med Lab, Zakladu Chem Farmaceutycznej, Szczecin, Poland
来源：
PRZEMYSL CHEMICZNY | 2023年 / 102卷 / 08期
关键词：
mesoporous silica; drug delivery system; steroids; pain; GLUCOCORTICOID THERAPY;
D O I：
10.15199/62.2023.8.4
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A review, with 40 refs., of use of mesoporous silicas as the carriers for anti-inflammatory steroid drugs such as dexamethasone, fluticasone propionate, mometasone furoate, and betamethasone sodium phosphate. The advantages resulting from the use of mesoporous silicas as the drug carriers were mainly ascribed to the drug biological availability improvement. The latter was the result of the acceleration of dissolution kinetics of drug adsorbed onto the large surface area of mesoporous adsorbent.
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页码：803 / 806
页数：4
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