A Comprehensive Mini Review on the Natural Product Bacopa monnieri for the Management of Alzheimer's Disease

被引:2
|
作者
Jain, Naman [1 ]
Tambekar, Omkar [1 ]
Goel, Tanvi [1 ]
Bodhankar, Subhash Laxmanrao [2 ]
Bansode, Deepali Amol [3 ]
机构
[1] Bharati Vidyapeeth Univ, Poona Coll Pharm, Pune 411038, Maharashtra, India
[2] Bharati Vidyapeeth Univ, Dept Pharmacol, Poona Coll Pharm, Pune 411038, Maharashtra, India
[3] Bharati Vidyapeeth Univ, Dept Pharmaceut Chem, Poona Coll Pharm, Pune 411038, Maharashtra, India
来源
NATURAL PRODUCTS JOURNAL | 2024年 / 14卷 / 02期
关键词
Bacopa monnieri; chemistry; alzheimer's disease; In vivo; In vitro; In silico models; BACOSIDE-A; MEMORY; MEMANTINE; PERFORMANCE; DYSFUNCTION; EXTRACTS;
D O I
10.2174/2210315514666230626161007
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Central nervous system disorders are expected to profoundly impact the global healthcare needs of the human community in this era. Senile decay of neurons is (Alzheimers Disease) AD. The hallmark of the pathophysiology of AD disease has two pivotal features: extracellular beta-amyloid deposition and intracellular tau hyperphosphorylation. New medicine-based psychoactive treatments have met with modest effectiveness due to the multifactorial nature of these diseases. As a result, there is an increasing need for new products that can address various receptors and enhance behavioral abilities independently or in tandem with traditional medications. Herbal products focused on conventional expertise have recently been widely popular in developed and developing countries. Ayurveda is a medical science that deals with the treatment of diseases using naturally occurring plant products. Ayurveda claims to have a large number of neuroprotective herbs. This review discusses the pharmacological effects and therapeutic properties of In vivo, In vitro, In silico and human clinical trials of (Bacopa monnieri) BM against AD.
引用
收藏
页码:2 / 13
页数:12
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