A Comprehensive Mini Review on the Natural Product Bacopa monnieri for the Management of Alzheimer's Disease

被引:2
|
作者
Jain, Naman [1 ]
Tambekar, Omkar [1 ]
Goel, Tanvi [1 ]
Bodhankar, Subhash Laxmanrao [2 ]
Bansode, Deepali Amol [3 ]
机构
[1] Bharati Vidyapeeth Univ, Poona Coll Pharm, Pune 411038, Maharashtra, India
[2] Bharati Vidyapeeth Univ, Dept Pharmacol, Poona Coll Pharm, Pune 411038, Maharashtra, India
[3] Bharati Vidyapeeth Univ, Dept Pharmaceut Chem, Poona Coll Pharm, Pune 411038, Maharashtra, India
来源
NATURAL PRODUCTS JOURNAL | 2024年 / 14卷 / 02期
关键词
Bacopa monnieri; chemistry; alzheimer's disease; In vivo; In vitro; In silico models; BACOSIDE-A; MEMORY; MEMANTINE; PERFORMANCE; DYSFUNCTION; EXTRACTS;
D O I
10.2174/2210315514666230626161007
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Central nervous system disorders are expected to profoundly impact the global healthcare needs of the human community in this era. Senile decay of neurons is (Alzheimers Disease) AD. The hallmark of the pathophysiology of AD disease has two pivotal features: extracellular beta-amyloid deposition and intracellular tau hyperphosphorylation. New medicine-based psychoactive treatments have met with modest effectiveness due to the multifactorial nature of these diseases. As a result, there is an increasing need for new products that can address various receptors and enhance behavioral abilities independently or in tandem with traditional medications. Herbal products focused on conventional expertise have recently been widely popular in developed and developing countries. Ayurveda is a medical science that deals with the treatment of diseases using naturally occurring plant products. Ayurveda claims to have a large number of neuroprotective herbs. This review discusses the pharmacological effects and therapeutic properties of In vivo, In vitro, In silico and human clinical trials of (Bacopa monnieri) BM against AD.
引用
收藏
页码:2 / 13
页数:12
相关论文
共 50 条
  • [1] A Computational Study of Natural Compounds from Bacopa monnieri in the Treatment of Alzheimer's Disease
    Jamal, Qazi M. S.
    Siddiqui, Mughees U.
    Alharbi, Ali H.
    Albejaidi, Fahad
    Akhtar, Salman
    Alzohairy, Mohammad A.
    Kamal, Mohammad A.
    Kesari, Kavindra K.
    CURRENT PHARMACEUTICAL DESIGN, 2020, 26 (07) : 790 - 800
  • [2] Brahmi (Bacopa monnieri): An ayurvedic herb against the Alzheimer's disease
    Dubey, Tushar
    Chinnathambi, Subashchandrabose
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2019, 676
  • [3] Effect of Bacopa monnieri on Cognitive functions in Alzheimer's disease patients
    Goswami, Shishir
    Saoji, Anand
    Kumar, Navneet
    Thawani, Vijay
    Tiwari, Meenal
    Thawani, Manasi
    INTERNATIONAL JOURNAL OF COLLABORATIVE RESEARCH ON INTERNAL MEDICINE & PUBLIC HEALTH, 2011, 3 (04) : 285 - 293
  • [4] Cognitive enhancement and neuroprotective effects of Bacopa monnieri in Alzheimer's disease model
    Uabundit, Nongnut
    Wattanathorn, Jintanaporn
    Mucimapura, Supaporn
    Ingkaninan, Kornkanok
    JOURNAL OF ETHNOPHARMACOLOGY, 2010, 127 (01) : 26 - 31
  • [5] A Comprehensive Review on Preclinical Evidence-based Neuroprotective Potential of Bacopa monnieri against Parkinson's Disease
    Goyal, Ahsas
    Gopika, Sainu
    Kumar, Abhishek
    Garabadu, Debapriya
    CURRENT DRUG TARGETS, 2022, 23 (09) : 889 - 901
  • [6] Memory Protecting Herbs: Centella asiatica and Bacopa monnieri in the Fight Against Alzheimer's Disease
    Deore, Sharada L.
    Kide, Anjali A.
    Baviskar, Bhushan A.
    Khadabadi, Somshekhar S.
    Shende, Bhavana A.
    REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, 2023, 33 (06): : 1263 - 1273
  • [7] Bacopa monnieri phytochemicals as promising BACE1 inhibitors for Alzheimer’s disease therapy
    Satyam Sangeet
    Arshad Khan
    Scientific Reports, 15 (1)
  • [8] Memory Protecting Herbs: Centella asiatica and Bacopa monnieri in the Fight Against Alzheimer's Disease
    Sharada L. Deore
    Anjali A. Kide
    Bhushan A. Baviskar
    Somshekhar S. Khadabadi
    Bhavana A. Shende
    Revista Brasileira de Farmacognosia, 2023, 33 (6) : 1263 - 1273
  • [9] Use of Bacopa monnieri in the Treatment of Dementia Due to Alzheimer Disease: Systematic Review of Randomized Controlled Trials
    Basheer, Aneesh
    Agarwal, Ayush
    Mishra, Biswamohan
    Gupta, Anu
    Srivastava, Madakasira Vasantha Padma
    Kirubakaran, Richard
    Vishnu, Venugopalan
    INTERACTIVE JOURNAL OF MEDICAL RESEARCH, 2022, 11 (02):
  • [10] Effectiveness of Bacopa Monnieri (Brahmi) in the management of schizophrenia: a systematic review
    Ayilara, Gideon Opeyemi
    Owoyele, Bamidele Victor
    NUTRITIONAL NEUROSCIENCE, 2024,