Rh(III)-Catalyzed Oxidative C-H Activation/Annulation of Salicylaldehydes with Masked Enynes for the Synthesis of Chromones

被引：4
|
作者：
Li, Bo [1 ,2 ]
Zhu, Jianping [1 ,2 ]
Zheng, Xia [1 ,2 ]
Ti, Wenqing [1 ,2 ]
Huang, Yue [3 ]
Yao, Hequan [1 ,2 ]
机构：
[1] China Pharmaceut Univ, State Key Lab Nat Med SKLNM, Nanjing 210009, Peoples R China
[2] China Pharmaceut Univ, Sch Pharm, Dept Med Chem, Nanjing 210009, Peoples R China
[3] China Pharmaceut Univ, Sch Sci, Dept Organ Chem, Nanjing 210009, Peoples R China
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2023年 / 88卷 / 01期
基金：
中国国家自然科学基金;
关键词：
ONE-POT SYNTHESIS; ANTIANAPHYLACTIC AGENTS; CATALYZED ALKENE; RHODIUM; CLEAVAGE; ALKYNES; ANNULATION; ALDEHYDES; HYDROACYLATION; CYCLOPROPENES;
D O I：
10.1021/acs.joc.2c02557
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A rhodium(III)-catalyzed oxidative C-H activation/annulation of salicylaldehydes with propargylic acetates has been developed for the regioselective synthesis of 3-vinyl chromones in good yields with broad functional group tolerance. 3-Vinyl chromones were converted into biologically active benzo[c]xanthone by I2-mediated oxidative electrocyclization.
引用
收藏
页码：548 / 558
页数：11
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