Tumor-targeted nanoflowers regulate glutamine metabolism and amplify oxidative stress for synergistic therapy

被引：3

作者：

Wang, Mengzhen ^{[1
]}

Wang, Kaixian ^{[1
]}

Liu, Xiaohan ^{[1
]}

Shi, Mingwan ^{[1
]}

Zhang, Huiwen ^{[1
]}

Zhang, Xia ^{[1
]}

Wei, Ruyue ^{[1
]}

Li, Na ^{[1
]}

Pan, Wei ^{[1
]}

Tang, Bo ^{[1
]}

机构：

[1] Shandong Normal Univ, Coll Chem Chem Engn & Mat Sci, Collaborat Innovat Ctr Functionalized Probes Chem, Inst Mol & Nano Sci,Key Lab Mol & Nano Probes,Mini, Jinan 250014, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 42期

基金：

中国国家自然科学基金;

关键词：

Amino acids - Metabolism - Tumors;

D O I：

10.1039/d3cc00487b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We designed and synthesized tumor-targeted nanoflowers to inhibit glutamine metabolism and amplify oxidative stress, which could synergistically suppress tumor growth.

引用

页码：6375 / 6378

页数：4

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