Tumor-targeted nanoflowers regulate glutamine metabolism and amplify oxidative stress for synergistic therapy

被引：3
|
作者：
Wang, Mengzhen [1 ]
Wang, Kaixian [1 ]
Liu, Xiaohan [1 ]
Shi, Mingwan [1 ]
Zhang, Huiwen [1 ]
Zhang, Xia [1 ]
Wei, Ruyue [1 ]
Li, Na [1 ]
Pan, Wei [1 ]
Tang, Bo [1 ]
机构：
[1] Shandong Normal Univ, Coll Chem Chem Engn & Mat Sci, Collaborat Innovat Ctr Functionalized Probes Chem, Inst Mol & Nano Sci,Key Lab Mol & Nano Probes,Mini, Jinan 250014, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 42期
基金：
中国国家自然科学基金;
关键词：
Amino acids - Metabolism - Tumors;
D O I：
10.1039/d3cc00487b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We designed and synthesized tumor-targeted nanoflowers to inhibit glutamine metabolism and amplify oxidative stress, which could synergistically suppress tumor growth.
引用
收藏
页码：6375 / 6378
页数：4
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