Vinylogous propargylation of α,α-dicyanoalkenes: construction of an all-carbon quaternary center

被引：0
|
作者：
Lu, Shuhui [1 ]
Zhao, Yujie [1 ]
Xie, Su [1 ]
Li, Wei [1 ]
Li, Shi-Wu [1 ]
机构：
[1] Shihezi Univ, Sch Chem & Chem Engn, Key Lab Green Proc Chem Engn Xinjiang Bingtuan, Shihezi 832000, Xinjiang Uygur, Peoples R China
来源：
NEW JOURNAL OF CHEMISTRY | 2023年 / 47卷 / 46期
基金：
中国国家自然科学基金;
关键词：
ACETYLENE;
D O I：
10.1039/d3nj04646j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The first highly efficient vinylogous propargylation of alpha,alpha-dicyanoalkenes catalyzed by a copper catalyst to construct an all-carbon quaternary center with 3-ethynyl-2-oxoindolin-3-yl acetates is reported. The corresponding products with an all-carbon quaternary center were obtained in moderate to excellent yields (up to 92%). In addition, a gram-scale reaction and derivative transformations have also been achieved. Vinylogous propargylation of alpha,alpha-dicyanoalkenes for construction of an all-carbon quaternary center.
引用
收藏
页码：21155 / 21158
页数：4
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