Synthesis and Characterization of Benzimidazole Derivatives and Evaluation of Antimicrobial activity

被引:0
|
作者
Vyas, Kamal Kant [1 ]
Rajpurohit, Sangeeta [2 ]
Vaishnav, Yudhishthir [1 ]
机构
[1] JNVU Jodhpur, Dept Chem, Jodhpur 342001, Rajasthan, India
[2] Lachoo Mem Coll, Organ Iab, Jodhpur 342001, Rajasthan, India
关键词
Benzimidazole; Antibacterial; Antifungal; ANTIBACTERIAL ACTIVITY;
D O I
10.13005/ojc/390424
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A series of benzimidazole derivatives were synthesized for this investigation. NMR and IR spectrum analysis as well as carbon, hydrogen, and nitrogen studies were used to characterize these novel synthesized derivatives. Antibacterial and antifungal tests were conducted on all of the newly synthesized compounds. Ciprofloxacin and fluconazole were utilized as reference medications in antibacterial and antifungal research, respectively. The microbiological assay revealed that the compounds show promising antibacterial and antifungal activity.
引用
收藏
页码:996 / 1001
页数:6
相关论文
共 50 条
  • [21] Synthesis, characterization and biological evaluation of novel benzimidazole derivatives
    Mahmood, Khalid
    Akhter, Zareen
    Asghar, Muhammad Adeel
    Mirza, Bushra
    Ismail, Hammad
    Liaqat, Faroha
    Kalsoom, Saima
    Ashraf, Ahmad Raza
    Shabbir, Muhammad
    Qayyum, Muhammad Abdul
    McKee, Vickie
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2020, 38 (06): : 1670 - 1682
  • [22] Evaluation of antimicrobial activity of glycinate and carbonate derivatives of cholesterol: Synthesis and characterization
    Sribalan, Rajendran
    Padmini, Vediappen
    Lavanya, Andiappan
    Ponnuvel, Kandasamy
    SAUDI PHARMACEUTICAL JOURNAL, 2016, 24 (06) : 658 - 668
  • [23] Synthesis, characterization and evaluation of analgesic activity of some 5-nitro benzimidazole derivatives
    Sravanthi, M.
    Nagaraju, N.
    Manikanta, K.
    Mogalabi, S.
    Eswaraiah, Chinna
    Bardalai, Dipankar
    Journal of Chemical and Pharmaceutical Research, 2012, 4 (08) : 3832 - 3836
  • [24] Synthesis, physicochemical properties and antimicrobial activity of some new benzimidazole derivatives
    Ansari, K. F.
    Lal, C.
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2009, 44 (10) : 4028 - 4033
  • [25] Synthesis and Antimicrobial Activity Evaluation of Homodrimane Sesquiterpenoids with a Benzimidazole Unit
    Lungu, Lidia
    Blaja, Svetlana
    Cucicova, Caleria
    Ciocarlan, Alexandru
    Barba, Alic
    Kulcitki, Veaceslav
    Shova, Sergiu
    Vornicu, Nicoleta
    Geana, Elisabeta-Irina
    Mangalagiu, Ionel I.
    Aricu, Aculina
    MOLECULES, 2023, 28 (03):
  • [26] SYNTHESIS AND ANTIMICROBIAL EVALUATION OF SOME NEW CHIRAL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES
    Shelar, A. R.
    Manvi, F. V.
    Shet, L. S.
    Taranalli, A. D.
    Bagave, Rashmi
    Mahesh
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2008, 18 (02) : 179 - 180
  • [27] Synthesis, Characterization, and Antimicrobial Activity of Silver(I) and Copper(II) Complexes of Phosphate Derivatives of Pyridine And Benzimidazole
    Kalinowska-Lis, Urszula
    Szewczyk, Eligia M.
    Checinska, Lilianna
    Wojciechowski, Jakub M.
    Wolf, Wojciech M.
    Ochocki, Justyn
    CHEMMEDCHEM, 2014, 9 (01) : 169 - 176
  • [28] Synthesis, Characterization, Antimicrobial Activity and Molecular Docking Studies of New Benzimidazole, Benzoxazole, Imidazole and Tetrazole Derivatives
    Arulmurugan, Subramaniyan
    Kavitha, Helen P.
    ORIENTAL JOURNAL OF CHEMISTRY, 2020, 36 (04) : 672 - 679
  • [29] Synthesis and evaluation of some new benzimidazole derivatives as potential antimicrobial agents
    Ansari, K. F.
    Lal, C.
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2009, 44 (05) : 2294 - 2299
  • [30] Synthesis, Characterization and Antimicrobial Activity of Piperidine Derivatives
    Zafar, Shaista
    Akhtar, Shamim
    Ali, Syed Imran
    Mushtaq, Nausheen
    Naeem, Sabahat
    Ali, Mohsin
    JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN, 2019, 41 (02): : 363 - 367