A two-photon fluorescent probe for formaldehyde detection and regeneration in living cells

被引：12
|
作者：
Song, Qi [1 ]
Liu, Zhiqiang [2 ]
Niu, Jie [2 ]
Zheng, Bowen [1 ]
Hao, Jingcheng [1 ]
Jiang, Jie [1 ,3 ]
机构：
[1] Shandong Univ, Sch Chem & Chem Engn, Key Lab Colloid & Interface Chem, Minist Educ, Jinan 250100, Peoples R China
[2] Shandong Univ, State Key Lab Crystal Mat, Jinan 250100, Shandong, Peoples R China
[3] Shandong Univ, Shenzhen Res Inst, Shenzhen 518057, Peoples R China
来源：
JOURNAL OF MATERIALS CHEMISTRY B | 2023年 / 11卷 / 20期
关键词：
IMAGING FORMALDEHYDE;
D O I：
10.1039/d3tb00158j
中图分类号：
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号：
0805 ; 080501 ; 080502 ;
摘要：
A two-photon excited fluorescent probe CMB-1 has been rationally developed for the detection and regeneration of formaldehyde based on a novel nucleophilic addition of a secondary amine to FA and subsequential alcoholysis reactivity mechanism. It enables a specific turn-on response towards formaldehyde and facilitates the monitoring of exogenous and endogenous formaldehyde in living cells via both one- and two-photon microscopy, with minimal influence on its native homeostasis and local concentration.
引用
收藏
页码：4408 / 4415
页数：8
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