Recent advances in the metal-catalyzed asymmetric alkene hydrogenation of cyclic conjugated carbonyl compounds

The transition metal-catalyzed asymmetric hydrogenation of carbon-carbon double bonds is recognized as one of the most straightforward methods for the preparation of stereopure compounds. Chiral cyclic motifs have widespread applications in organic synthesis and can also be prepared via this strategy. This review summarizes the recent advances (2016-2023) in the stereoselective metal-catalyzed hydrogenation of cyclic alpha,beta-unsaturated ketones, lactams and lactones since considerable developments in this regard were made. The applications of these methodologies in synthesis are also outlined where relevant. This review summarizes the recent advances (2016-2023) in the stereoselective metal-catalyzed hydrogenation of cyclic alpha,beta-unsaturated ketones, lactams and lactones since considerable developments were made. Where possible the application of these methodologies in synthesis is outlined.