Imaging the ANGPTL3/8-mediated regulation of lipoprotein lipase in the heart

被引:5
|
作者
Yang, Ye [1 ,2 ]
Jung, Hyesoo [1 ]
Konrad, Robert J. [3 ]
Fong, Loren G. [1 ]
Young, Stephen G. [1 ,2 ]
机构
[1] Univ Calif Los Angeles, Dept Med, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Dept Human Genet, Los Angeles, CA 90095 USA
[3] Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN USA
关键词
D O I
10.1016/j.jlr.2023.100467
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页数:1
相关论文
共 50 条
  • [21] Effects of exercise training on ANGPTL3/8 and ANGPTL4/8 and their associations with cardiometabolic traits
    Hoffmann, William G.
    Chen, Yan Q.
    Schwartz, Charles S.
    Barber, Jacob L.
    Dev, Prasun K.
    Reasons, Riley J.
    Maravi, Juan S. Miranda
    Armstrong, Bridget
    Gerszten, Robert E.
    Silbernagel, Guenther
    Konrad, Robert J.
    Bouchard, Claude
    Sarzynski, Mark A.
    JOURNAL OF LIPID RESEARCH, 2024, 65 (02)
  • [22] Angptl3 Deficiency Is Associated With Increased Insulin Sensitivity, Lipoprotein Lipase Activity, and Decreased Serum Free Fatty Acids
    Robciuc, Marius R.
    Maranghi, Marianna
    Lahikainen, Anna
    Rader, Daniel
    Bensadoun, Andre
    Oorni, Katariina
    Metso, Jari
    Minicocci, Ilenia
    Ciociola, Ester
    Ceci, Fabrizio
    Montali, Anna
    Arca, Marcello
    Ehnholm, Christian
    Jauhiainen, Matti
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2013, 33 (07) : 1706 - 1713
  • [23] Protein region important for regulation of lipid metabolism in angiopoietin-like 3 (ANGPTL3) -: ANGPTL3 is cleaved and activated in vivo
    Ono, M
    Shimizugawa, T
    Shimamura, M
    Yoshida, K
    Noji-Sakikawa, C
    Ando, Y
    Koishi, R
    Furukawa, H
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (43) : 41804 - 41809
  • [24] Serum ANGPTL8 and ANGPTL3 as Predictors of Triglyceride Elevation in Adult Women
    Stefanska, Anna
    Bergmann, Katarzyna
    Krintus, Magdalena
    Kuligowska-Prusinska, Magdalena
    Murawska, Karolina
    Sypniewska, Grazyna
    METABOLITES, 2022, 12 (06)
  • [25] Angiopoietin-Like Protein 3 (ANGPTL3) Modulates Lipoprotein Metabolism and Dyslipidemia
    Chen, Pei-Yi
    Gao, Wan-Yun
    Liou, Je-Wen
    Lin, Ching-Yen
    Wu, Ming-Jiuan
    Yen, Jui-Hung
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (14)
  • [26] Associations of Circulating ANGPTL3, C-Terminal Domain-Containing ANGPTL4, and ANGPTL3/8 and ANGPTL4/8 Complexes with LPL Activity, Diabetes, Inflammation, and Cardiovascular Mortality
    Silbernagel, Guenther
    Chen, Yan Q.
    Li, Hongxia
    Lemen, Deven
    Wen, Yi
    Zhen, Eugene Y.
    Rief, Martin
    Kleber, Marcus E.
    Delgado, Graciela E.
    Sarzynski, Mark A.
    Qian, Yue-Wei
    Schmidt, Boerge
    Erbel, Raimund
    Trampisch, Ulrike S.
    Moissl, Angela P.
    Rudolf, Henrik
    Schunkert, Heribert
    Stang, Andreas
    Maerz, Winfried
    Trampisch, Hans J.
    Scharnagl, Hubert
    Konrad, Robert J.
    CIRCULATION, 2025, 151 (03) : 218 - 234
  • [27] Angptl3 Regulates Hepatic Lipoprotein Production: A New Model For Lipid Lowering?
    Burks, Kendall H.
    Xie, Yan
    Pondugula, Santhi
    Neufeld, Thomas
    Alisio, Arturo
    Davidson, Nicholas O.
    Stitziel, Nathan O.
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2022, 42
  • [28] Identification of a New Functional Domain in Angiopoietin-like 3 (ANGPTL3) and Angiopoietin-like 4 (ANGPTL4) Involved in Binding and Inhibition of Lipoprotein Lipase (LPL)
    Lee, E-Chiang
    Desai, Urvi
    Gololobov, Gennady
    Hong, Seokjoo
    Feng, Xiao
    Yu, Xuan-Chuan
    Gay, Jason
    Wilganowski, Nat
    Gao, Cuihua
    Du, Ling-Ling
    Chen, Joan
    Hu, Yi
    Zhao, Sharon
    Kirkpatrick, Laura
    Schneider, Matthias
    Zambrowicz, Brian P.
    Landes, Greg
    Powell, David R.
    Sonnenburg, William K.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (20) : 13735 - 13745
  • [29] LDL-Cholesterol Reduction by ANGPTL3 Inhibition in Mice Is Dependent on Endothelial Lipase
    Wu, Liya
    Soundarapandian, Mangala M.
    Castoreno, Adam B.
    Millar, John S.
    Rader, Daniel J.
    CIRCULATION RESEARCH, 2020, 127 (08) : 1112 - 1114
  • [30] TRIACYLGLYCEROL-RICH LIPOPROTEINS INFLUENCE THE INACTIVATION OF LIPOPROTEIN LIPASE BY ANGPTL 3 AND ANGPTL 4
    Nilsson, S.
    Larsson, M.
    Lookene, A.
    Heeren, J.
    Olivecrona, G.
    ATHEROSCLEROSIS SUPPLEMENTS, 2009, 10 (02)