Chitosan-Based Self-Healing Hydrogel: From Fabrication to Biomedical Application

被引：17
|
作者：
Pan, Siyu [1 ]
Zhu, Chongyu [2 ]
Wu, Yuwei [3 ]
Tao, Lei [1 ]
机构：
[1] Tsinghua Univ, Dept Chem, Key Lab Bioorgan Phosphorus Chem & Chem Biol, Minist Educ, Beijing 100084, Peoples R China
[2] Donghua Univ, Coll Chem & Chem Engn, Key Lab Sci & Technol Ecotext, Minist Educ, Shanghai 201620, Peoples R China
[3] Peking Univ, Sch & Hosp Stomatol, Dent Ctr 2, Beijing 100101, Peoples R China
来源：
POLYMERS | 2023年 / 15卷 / 18期
关键词：
chitosan; self-healing; hydrogel; fabrication; tissue engineering; customized drug delivery; smart biosensors; three/four dimensional (3D/4D) printing; PLATELET-RICH PLASMA; ACID-BASED HYDROGELS; INJECTABLE HYDROGELS; GLYCOL CHITOSAN; DRUG-DELIVERY; CROSS-LINKING; THERAPY; DRESSINGS; RELEASE;
D O I：
10.3390/polym15183768
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Biocompatible self-healing hydrogels are new-generation smart soft materials that hold great promise in biomedical fields. Chitosan-based self-healing hydrogels, mainly prepared via dynamic imine bonds, have attracted broad attention due to their mild preparation conditions, excellent biocompatibility, and self-recovery ability under a physiological environment. In this review, we present a comprehensive overview of the design and fabrication of chitosan-based self-healing hydrogels, and summarize their biomedical applications in tissue regeneration, customized drug delivery, smart biosensors, and three/four dimensional (3D/4D) printing. Finally, we will discuss the challenges and future perspectives for the development of chitosan-based self-healing hydrogels in the biomedical field.
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收藏
页数：20
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