Ischemic stroke;
Carotid;
Stroke risk prediction;
Deep learning;
3D image segmentation;
ARTERY SEGMENTATION;
ANGIOGRAPHY;
NETWORK;
LUMEN;
NET;
D O I:
10.1007/s12539-023-00583-x
中图分类号:
Q [生物科学];
学科分类号:
07 ;
0710 ;
09 ;
摘要:
Stroke is still the World's second major factor of death, as well as the third major factor of death and disability. Ischemic stroke is a type of stroke, in which early detection and treatment are the keys to preventing ischemic strokes. However, due to the limitation of privacy protection and labeling difficulties, there are only a few studies on the intelligent automatic diagnosis of stroke or ischemic stroke, and the results are unsatisfactory. Therefore, we collect some data and propose a 3D carotid Computed Tomography Angiography (CTA) image segmentation model called CA-UNet for fully automated extraction of carotid arteries. We explore the number of down-sampling times applicable to carotid segmentation and design a multi-scale loss function to resolve the loss of detailed features during the process of down-sampling. Moreover, based on CA-Unet, we propose an ischemic stroke risk prediction model to predict the risk in patients using their 3D CTA images, electronic medical records, and medical history. We have validated the efficacy of our segmentation model and prediction model through comparison tests. Our method can provide reliable diagnoses and results that benefit patients and medical professionals.
机构:
Shanghai United Imaging Intelligence Co Ltd, Dept Res & Dev, Shanghai, Peoples R ChinaShanghai United Imaging Intelligence Co Ltd, Dept Res & Dev, Shanghai, Peoples R China
Wang, Xuechun
Meng, Yuting
论文数: 0引用数: 0
h-index: 0
机构:
Zhejiang Univ, Affiliated Hangzhou Peoples Hosp 1, Sch Med, Dept Radiol, Hangzhou, Peoples R China
Zhejiang Univ, Sch Med, Affiliated Hangzhou Peoples Hosp 1, Dept Neurol, Hangzhou, Peoples R ChinaShanghai United Imaging Intelligence Co Ltd, Dept Res & Dev, Shanghai, Peoples R China
Meng, Yuting
Dong, Zhijian
论文数: 0引用数: 0
h-index: 0
机构:
Xian Gaoxin Hosp, Dept Nucl Med, Xian, Shaanxi, Peoples R ChinaShanghai United Imaging Intelligence Co Ltd, Dept Res & Dev, Shanghai, Peoples R China
Dong, Zhijian
Cao, Zehong
论文数: 0引用数: 0
h-index: 0
机构:
Shanghai United Imaging Intelligence Co Ltd, Dept Res & Dev, Shanghai, Peoples R ChinaShanghai United Imaging Intelligence Co Ltd, Dept Res & Dev, Shanghai, Peoples R China
Cao, Zehong
He, Yichu
论文数: 0引用数: 0
h-index: 0
机构:
Shanghai United Imaging Intelligence Co Ltd, Dept Res & Dev, Shanghai, Peoples R ChinaShanghai United Imaging Intelligence Co Ltd, Dept Res & Dev, Shanghai, Peoples R China
He, Yichu
Sun, Tianyang
论文数: 0引用数: 0
h-index: 0
机构:
Shanghai United Imaging Intelligence Co Ltd, Dept Res & Dev, Shanghai, Peoples R ChinaShanghai United Imaging Intelligence Co Ltd, Dept Res & Dev, Shanghai, Peoples R China
Sun, Tianyang
Zhou, Qing
论文数: 0引用数: 0
h-index: 0
机构:
Shanghai United Imaging Intelligence Co Ltd, Dept Res & Dev, Shanghai, Peoples R ChinaShanghai United Imaging Intelligence Co Ltd, Dept Res & Dev, Shanghai, Peoples R China
Zhou, Qing
Niu, Guozhong
论文数: 0引用数: 0
h-index: 0
机构:
Zhejiang Univ, Sch Med, Affiliated Hangzhou Peoples Hosp 1, Dept Neurol, Hangzhou, Peoples R ChinaShanghai United Imaging Intelligence Co Ltd, Dept Res & Dev, Shanghai, Peoples R China
Niu, Guozhong
Ding, Zhongxiang
论文数: 0引用数: 0
h-index: 0
机构:
Zhejiang Univ, Affiliated Hangzhou Peoples Hosp 1, Sch Med, Dept Radiol, Hangzhou, Peoples R ChinaShanghai United Imaging Intelligence Co Ltd, Dept Res & Dev, Shanghai, Peoples R China
Ding, Zhongxiang
Shi, Feng
论文数: 0引用数: 0
h-index: 0
机构:
Shanghai United Imaging Intelligence Co Ltd, Dept Res & Dev, Shanghai, Peoples R ChinaShanghai United Imaging Intelligence Co Ltd, Dept Res & Dev, Shanghai, Peoples R China
Shi, Feng
Shen, Dinggang
论文数: 0引用数: 0
h-index: 0
机构:
Shanghai United Imaging Intelligence Co Ltd, Dept Res & Dev, Shanghai, Peoples R China
ShanghaiTech Univ, Sch Biomed Engn, Shanghai, Peoples R China
Shanghai Clin Res & Trial Ctr, Shanghai, Peoples R ChinaShanghai United Imaging Intelligence Co Ltd, Dept Res & Dev, Shanghai, Peoples R China
机构:
Univ Liverpool, Dept Math Sci, Liverpool, Merseyside, England
Natl Tsing Hua Univ, Ctr Cognit & Mind Sci, Hsinchu, Taiwan
Natl Tsing Hua Univ, Int Intercoll PhD Programme, Hsinchu, TaiwanUniv Liverpool, Dept Math Sci, Liverpool, Merseyside, England
Bal, Sukhdeep Singh
Chen, Ke
论文数: 0引用数: 0
h-index: 0
机构:
Univ Liverpool, Dept Math Sci, Liverpool, Merseyside, EnglandUniv Liverpool, Dept Math Sci, Liverpool, Merseyside, England
Chen, Ke
Yang, Fan-Pei Gloria
论文数: 0引用数: 0
h-index: 0
机构:
Natl Tsing Hua Univ, Ctr Cognit & Mind Sci, Hsinchu, Taiwan
Natl Tsing Hua Univ, Dept Foreign Languages & Literature, Hsinchu, Taiwan
Osaka Univ, Grad Sch Dent, Dept Radiol, Osaka, Japan
101,Sect 2,Guangfu Rd, Hsinchu, TaiwanUniv Liverpool, Dept Math Sci, Liverpool, Merseyside, England
Yang, Fan-Pei Gloria
Peng, Giia-Sheun
论文数: 0引用数: 0
h-index: 0
机构:
Natl Def Med Ctr, Triserv Gen Hosp, Dept Neurol, Taipei, Taiwan
Taipei Vet Gen Hosp, Dept Internal Med, Div Neurol, Hsinchu Branch, Hsinchu, TaiwanUniv Liverpool, Dept Math Sci, Liverpool, Merseyside, England