Total Synthesis of Ganoderma Meroterpenoids - Progresses since 2014

被引:5
|
作者
Kawamoto, Yuichiro [1 ]
Ito, Hisanaka [1 ]
机构
[1] Tokyo Univ Pharm & Life Sci, Sch Life Sci, 1432-1 Horinouchi, Hachioji, Tokyo, Japan
关键词
Ganoderma meroterpenoids; total synthesis; cascade reaction; tandem reaction; one-pot operation; ENANTIOSELECTIVE TOTAL-SYNTHESIS; FRIEDEL-CRAFTS CYCLIALKYLATIONS; ASYMMETRIC TOTAL-SYNTHESIS; AEROBIC DEHYDROGENATION; POLYCYCLIC MEROTERPENOIDS; SECONDARY ALCOHOLS; ORGANIC HALIDES; CARBON-MONOXIDE; ACID; OXIDATION;
D O I
10.1002/ajoc.202300633
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Meroterpenoids isolated from fungi of the Ganoderma family have received much attention owing to their unique structures and diverse biological activities. A number of Ganoderma meroterpenoids have been isolated since 2000 and many total syntheses and synthetic studies have since been reported. In this review, we highlight fifteen total syntheses conducted from 2014 to 2023 of polycyclic Ganoderma meroterpenoids classified according to the connection pattern of the dihydroquinone with the terpenoid structure. The selected studies illustrate how the molecular complexity was constructed by unique tactics.
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页数:19
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