Preview Fecal transfers from children on the ketogenic diet mimic the anti-seizure effect in mice

被引:1
|
作者
Prast-Nielsen, Stefanie [1 ]
机构
[1] Karolinska Inst, Ctr Translat Microbiome Res, Dept Microbiol Tumor & Cell Biol, Stockholm, Sweden
来源
CELL REPORTS | 2023年 / 42卷 / 12期
关键词
D O I
10.1016/j.celrep.2023.113570
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The ketogenic diet (KD) mediates its anti-seizure effect through the gut microbiota in epilepsy mouse models.(1) Lum et al.(2) demonstrated that fecal microbiota from children with epilepsy treated with the KD decreases seizure susceptibility in mice after transfer.
引用
收藏
页数:2
相关论文
共 38 条
  • [21] Neuroprotective effect of a medium-chain triglyceride ketogenic diet on MPTP-induced Parkinson’s disease mice: a combination of transcriptomics and metabolomics in the substantia nigra and fecal microbiome
    Wenlong Zhang
    Shiyu Chen
    Xingting Huang
    Huichun Tong
    Hongxin Niu
    Lingli Lu
    Cell Death Discovery, 9
  • [22] TRANSFER OF THE FECAL MICROBIAL-FLORA FROM HOLOXENIC PIGLETS AND ADULT PIGS TO AXENIC PIGLETS AND AXENIC ADULT MICE - EFFECT OF THE ANIMAL HOST AND OF THE DIET ON THE FECAL MICROBIAL PATTERN OF THESE ANIMALS
    DUCLUZEAU, R
    RAPINE, P
    COURVALIN, C
    RAIBAUD, P
    ANNALES DE MICROBIOLOGIE, 1978, B129 (04): : 597 - 612
  • [23] The effect of a ketogenic diet on cannabidiol plasma concentration and seizure reduction in patients with Lennox- Gastaut syndrome or Dravet syndrome: Post-hoc analysis of data from the randomised controlled trials
    Landmark, C. Johannessen
    McCarter, M.
    Meinilid, H.
    Vyas, K.
    EPILEPSIA, 2024, 65 : 457 - 458
  • [24] EFFECT OF A MODIFIED AMERICAN DIET ON INTESTINAL INFLAMMATION IN SAMP1/YITFC (SAMP) MICE TRANSPLANTED WITH FECAL MATTER FROM A PATIENT WITH CROHN'S DISEASE
    Basson, Abigail R.
    Gomez-Nguyen, Adrian
    Warner, Alexandra N.
    Rodriguez-Palacios, Alexander
    Cominelli, Fabio
    GASTROENTEROLOGY, 2019, 156 (06) : S686 - S687
  • [25] An 8-Week, Low Carbohydrate, High Fat, Ketogenic Diet Enhanced Exhaustive Exercise Capacity in Mice Part 2: Effect on Fatigue Recovery, Post-Exercise Biomarkers and Anti-Oxidation Capacity
    Huang, Qingyi
    Ma, Sihui
    Tominaga, Takaki
    Suzuki, Katsuhiko
    Liu, Chunhong
    NUTRIENTS, 2018, 10 (10):
  • [26] Lactic acid bacteria isolated from kimchi to evaluate anti-obesity effect in high fat diet-induced obese mice
    Lee S.Y.
    Sekhon S.S.
    Ko J.H.
    Kim H.C.
    Kim S.Y.
    Won K.
    Ahn J.-Y.
    Lee K.
    Kim Y.-H.
    Toxicology and Environmental Health Sciences, 2018, 10 (1) : 11 - 16
  • [27] The Anti-Diabetic Effect of Non-Starch Polysaccharides Extracted from Wheat Beer on Diet/STZ-Induced Diabetic Mice
    Oumeddour, Dounya Zad
    Lin, Wen
    Lian, Chang
    Zhao, Lei
    Wang, Xinyi
    Zhao, Liang
    Guo, Liyun
    FOODS, 2024, 13 (17)
  • [28] Effect of Anti-Epileptic Drug Prophylaxis on Time to First Seizure Diagnosis in Children with Brain Tumors, Using National Medicaid Claims from 2009 to 2012
    Yun, M.
    Zhang, M.
    Basma, N.
    Khakoo, Y.
    Grinspan, Z.
    ANNALS OF NEUROLOGY, 2019, 86 : S31 - S32
  • [29] Anti-Obesity Effect of Diphlorethohydroxycarmalol Isolated from Brown Alga Ishige okamurae in High-Fat Diet-Induced Obese Mice
    Ding, Yuling
    Wang, Lei
    Im, SeungTae
    Hwang, Ouibo
    Kim, Hyun-Soo
    Kang, Min-Cheol
    Lee, Seung-Hong
    MARINE DRUGS, 2019, 17 (11)
  • [30] Effect Of Concomitant Enzyme-Inducing Anti-Seizure Drugs (EIASDS) On The Safety And Efficacy Of Adjunctive Perampanel In Patients Aged 4 To <12 Years With Partial-Onset Seizures (POS): Final Results From The 311 Core Study
    Milh, M.
    Flamini, R.
    Fogarasi, A.
    Phillips, S.
    Yoshitomi, S.
    Patten, A.
    Takase, T.
    Ngo, L. Y.
    EPILEPSIA, 2019, 60 : 24 - 24