Roles of microRNAs and exosomes in Helicobacter pylori associated gastric cancer

被引：8

作者：

Xu, Xiao-Han ^{[1
]}

Shao, Shu-Li ^{[2
]}

Guo, Dong ^{[2
]}

Ge, Li-Na ^{[3
]}

Wang, Zan ^{[1
]}

Liu, Peng ^{[2
]}

Tao, Yuan-Yong ^{[4
]}

机构：

[1] Weifang Med Univ, Sch Med Lab, Weifang 261053, Shandong, Peoples R China

[2] Weihai Municipal Hosp, Dept Cent Lab, Weihai 264200, Shandong, Peoples R China

[3] Dalian Med Univ, Sch Lab Med, Dalian 116044, Liaoning, Peoples R China

[4] Weifang Med Univ, Dept Lab Med, Affiliated Hosp, Weifang 261031, Shandong, Peoples R China

来源：

MOLECULAR BIOLOGY REPORTS | 2023年 / 50卷 / 01期

基金：

中国国家自然科学基金;

关键词：

Helicobacter pylori; Gastric cancer; Exosomes; Exosomal miRNAs; PROGRESSION; PROMOTES; DELIVERY; THERAPY; CELLS;

D O I：

10.1007/s11033-022-08073-x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Helicobacter pylori (H. pylori) is a common pathogen that infects more than half of the world's population. Its infection can not only lead to a variety of gastrointestinal diseases, such as chronic gastritis and gastric cancer (GC) but also be associated with many extra-gastrointestinal diseases. Exosomes, as a new intercellular information transmission medium, can carry biological signal molecules such as microRNAs (miRNAs) to regulate a variety of cellular physiological activities and are involved in multiple cancer processes. In this article, we provide a systematic review on the role of exosomal miRNAs in H. pylori-associated GC.

引用

页码：889 / 897

页数：9

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