Roles of microRNAs and exosomes in Helicobacter pylori associated gastric cancer

被引:8
|
作者
Xu, Xiao-Han [1 ]
Shao, Shu-Li [2 ]
Guo, Dong [2 ]
Ge, Li-Na [3 ]
Wang, Zan [1 ]
Liu, Peng [2 ]
Tao, Yuan-Yong [4 ]
机构
[1] Weifang Med Univ, Sch Med Lab, Weifang 261053, Shandong, Peoples R China
[2] Weihai Municipal Hosp, Dept Cent Lab, Weihai 264200, Shandong, Peoples R China
[3] Dalian Med Univ, Sch Lab Med, Dalian 116044, Liaoning, Peoples R China
[4] Weifang Med Univ, Dept Lab Med, Affiliated Hosp, Weifang 261031, Shandong, Peoples R China
基金
中国国家自然科学基金;
关键词
Helicobacter pylori; Gastric cancer; Exosomes; Exosomal miRNAs; PROGRESSION; PROMOTES; DELIVERY; THERAPY; CELLS;
D O I
10.1007/s11033-022-08073-x
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Helicobacter pylori (H. pylori) is a common pathogen that infects more than half of the world's population. Its infection can not only lead to a variety of gastrointestinal diseases, such as chronic gastritis and gastric cancer (GC) but also be associated with many extra-gastrointestinal diseases. Exosomes, as a new intercellular information transmission medium, can carry biological signal molecules such as microRNAs (miRNAs) to regulate a variety of cellular physiological activities and are involved in multiple cancer processes. In this article, we provide a systematic review on the role of exosomal miRNAs in H. pylori-associated GC.
引用
收藏
页码:889 / 897
页数:9
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