New bisbenzylisoquinoline alkaloid, isolation and structure elucidation from Cocculus pendulus

被引:1
|
作者
Sultani, Shaikh Ziauddin [1 ]
Anwar, Muhammad Aijaz [2 ]
Alam, Muhammad Shahab [3 ]
机构
[1] Govt Degree Sci & Commerce Coll, Dept Chem, Karachi, Pakistan
[2] Pakistan Council Sci & Ind Res PCSIR, Pharmaceut Res Ctr, Karachi, Pakistan
[3] Dawood Univ Engn & Technol, Dept Basic Sci Math & Humanities, Karachi, Pakistan
关键词
Bisbenzylisoquinoline alkaloids; 2N-methylkohatine; Kohatine; Cocculus pendulus;
D O I
10.1080/14786419.2022.2142790
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
This paper describes phytochemical studies on aerial part of the Cocculus pendulus, which led to the identification of a new ingredient namely, 2 N-methylkohatine (1) along with four reported compounds Kohatine (2), 1,2-Dehydrokohatine (3) and 5 ' Hhydroxyapateline (4). Structures of the all Compounds were elucidated by using 1 D and 2 D NMR and mass spectroscopy furthermore the structure of new Compound 1 was also proved by synthesize from compound 2 (Kohatine).
引用
收藏
页码:1347 / 1353
页数:7
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