Long-Term Outcome of Lower Extremity Bypass Surgery in Diabetic and Non-Diabetic Patients with Critical Limb-Threatening Ischaemia in Germany

被引:1
|
作者
Surmann, Johanna [1 ]
Meyer, Philipp [1 ]
Epple, Jasmin [2 ]
Schmitz-Rixen, Thomas [3 ]
Boeckler, Dittmar [1 ]
Grundmann, Reinhart T. [4 ]
Hinterseher, Irene
El Hage, Racha
机构
[1] Univ Hosp Heidelberg, Dept Vasc & Endovascular Surg, D-69120 Heidelberg, Germany
[2] Univ Hosp Frankfurt Main, Dept Vasc & Endovascular Surg, D-60596 Frankfurt, Germany
[3] Goethe Univ Frankfurt, Dept Vasc & Endovascular Surg, D-60629 Frankfurt, Germany
[4] German Soc Vasc Surg & Vasc Med, German Inst Vasc Healthcare Res DIGG, D-10115 Berlin, Germany
关键词
bypass surgery; open revascularisation; diabetes; critical limb-threatening ischaemia; peripheral artery disease; long-term survival; major amputation; INFRAINGUINAL BYPASS; REVASCULARIZATION;
D O I
10.3390/biomedicines12010038
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Aim: To present the short- and long-term outcomes of lower extremity bypass (LEB) surgery in patients with critical limb-threatening ischaemia (CLTI), comparing diabetic (DM) and non-diabetic (non-DM) patients. Methods: Retrospective analysis of anonymised data from a nationwide health insurance company (AOK). Data from 22,633 patients (DM: n = 7266; non-DM: n = 15,367; men: n = 14,523; women: n = 8110; mean patient age: 72.5 years), who underwent LEB from 2010 to 2015, were analysed. The cut-off date for follow-up was December 31, 2018 (mean follow-up period: 55 months). Results: Perioperative mortality was 10.0% for DM and 8.2% for non-DM (p < 0.001). Patients with crural/pedal bypasses (n = 8558) had a significantly higher perioperative mortality (10.3%) than those with above-the-knee (n = 7246; 5.8%; p < 0.001) and below-the-knee bypasses (n = 6829; 8.9%; p = 0.003). The 9-year survival rates in DM patients were significantly worse, at 21.5%, compared to non-DM, at 31.1% (p < 0.001). This applied to both PAD stage III (DM: 34.4%; non-DM: 45.7%; p < 0.001) and PAD stage IV (DM: 18.5%; non-DM: 25.0%; p < 0.001). Patients with crural/pedal bypasses had a significantly inferior survival rate (25.5%) compared to those with below-the-knee (27.7%; p < 0.001) and above-the-knee bypasses (31.7%; p < 0.001). Conclusion: Perioperative and long-term outcomes regarding survival and major amputation rate for CLTI patients undergoing LEB are consistently worse for DM patients compared to non-DM patients.
引用
收藏
页数:10
相关论文
共 50 条
  • [31] Long-term follow-up of diabetic and non-diabetic patients with chronic hepatitis C
    Li, Xiaofei
    Zhu, Feiyan
    LIVER INTERNATIONAL, 2021, 41 (01) : 230 - 230
  • [32] Long-term follow-up of diabetic and non-diabetic patients with chronic hepatitis C
    Ciancio, Alessia
    Ribaldone, Davide Giuseppe
    Sacco, Marco
    Saracco, Giorgio Maria
    LIVER INTERNATIONAL, 2021, 41 (03) : 640 - 640
  • [33] LONG-TERM INSULIN-TREATMENT IN 2 NON-DIABETIC PATIENTS
    ASPLUND, J
    AHLMARK, G
    GUNNARSSON, R
    OSTMAN, J
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1981, 246 (08): : 870 - 870
  • [34] Comparison of lower extremity atherosclerosis in diabetic and non-diabetic patients using multidetector computed tomography
    Ci He
    Jin-gang Yang
    Yun-ming Li
    Jian Rong
    Fei-zhou Du
    Zhi-gang Yang
    Ming Gu
    BMC Cardiovascular Disorders, 14
  • [35] Multiple Arterial Grafting During Coronary Artery Bypass Graft Surgery in Diabetic and Non-Diabetic Patients: A Short- and Long-Term Analysis at a Single Center
    Jasarevic, Miralem
    Krueger, Oskar
    Strathmann, Jan
    Jasarevic, Marinela
    Shehada, Sharaf-Eldin
    Piotrowski, Jarowit Adam
    Massoudy, Parwis
    Jakob, Heinz
    Kamler, Markus
    Akhyari, Payam
    Thielmann, Matthias
    JOURNAL OF CLINICAL MEDICINE, 2024, 13 (23)
  • [36] Comparison of lower extremity atherosclerosis in diabetic and non-diabetic patients using multidetector computed tomography
    He, Ci
    Yang, Jin-gang
    Li, Yun-ming
    Rong, Jian
    Du, Fei-zhou
    Yang, Zhi-gang
    Gu, Ming
    BMC CARDIOVASCULAR DISORDERS, 2014, 14
  • [37] Long-term Outcome after Thrombolysis for Acute Lower Limb Ischaemia
    Grip, O.
    Wanhainen, A.
    Acosta, S.
    Bjorck, M.
    EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY, 2017, 53 (06) : 853 - 861
  • [38] Predictors of outcome in diabetic patients undergoing infrapopliteal endovascular revascularization for chronic limb-threatening ischemia
    Yap, Trixie
    Silickas, Justinas
    Weerakkody, Ruwan
    Lea, Talia
    Santhirakumaran, Gowthanan
    Bremner, Laura
    Diamantopoulos, Athanasios
    Biasi, Lukla
    Thomas, Stephen
    Zayed, Hany
    Patel, Sanjay D.
    JOURNAL OF VASCULAR SURGERY, 2022, 75 (02) : 618 - 624
  • [39] The management and outcome of critical limb ischaemia in diabetic patients: Results of a national survey
    daSilva, AF
    Desgranges, P
    Holdsworth, J
    Harris, PL
    McCollum, P
    Jones, SM
    Beard, J
    Callam, M
    DIABETIC MEDICINE, 1996, 13 (08) : 726 - 728
  • [40] Discrepancy in opioid prescription patterns for Black or African American patients following lower extremity bypass surgery for chronic limb-threatening ischemia
    Lavanga, Elizabeth
    Samaan, Fadi
    Dehaven, Christopher
    Ramirez, Maria C. Castello
    Aziz, Faisal
    JOURNAL OF VASCULAR SURGERY, 2025, 81 (01)