Knockout of Sod2 accelerates KrasG12D-driven formation of pancreatic cancerous lesions

被引:0
|
作者
Martinez, Alicia K. Fleming
Edenfield, Brandy H.
Esposito, Irene
Storz, Peter
机构
关键词
D O I
10.1158/1538-7445.AM2023-4775
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
4775
引用
收藏
页数:2
相关论文
共 50 条
  • [31] Somatostatin Receptor SST2 Haploinsufficiency Accelerates KRASG12d-Initiated Pancreatic Carcinogenesis by Promoting Inflammation
    Chalabi, Mounira
    Cassant-Sourdy, Stephanie
    Lulka, Hubert
    Blanc, Isabelle
    Al Saati, Talal
    Garmy-Susini, Barbara
    Dufresne, Marlene
    Guillermet-Guibert, Julie
    Pyronnet, Stephane
    Bousquet, Corinne
    GASTROENTEROLOGY, 2013, 144 (05) : S65 - S65
  • [32] Opposing role of Notch1 and Notch2 in a KrasG12D-driven murine non-small cell lung cancer model
    A Baumgart
    P K Mazur
    M Anton
    M Rudelius
    K Schwamborn
    A Feuchtinger
    K Behnke
    A Walch
    R Braren
    C Peschel
    J Duyster
    J T Siveke
    T Dechow
    Oncogene, 2015, 34 : 578 - 588
  • [33] ANGPTL4 accelerates KRASG12D-Induced acinar to ductal metaplasia and pancreatic carcinogenesis
    Yan, Hong Hua
    Jung, Kyung Hee
    Lee, Ji Eun
    Son, Mi Kwon
    Fang, Zhenghuan
    Park, Jung Hee
    Kim, Soo Jung
    Kim, Ju Young
    Lim, Ju Han
    Hong, Soon-Sun
    CANCER LETTERS, 2021, 519 : 185 - 198
  • [34] Opposing role of Notch1 and Notch2 in a KrasG12D-driven murine non-small cell lung cancer model
    Baumgart, A.
    Mazur, P. K.
    Anton, M.
    Rudelius, M.
    Schwamborn, K.
    Feuchtinger, A.
    Behnke, K.
    Walch, A.
    Braren, R.
    Peschel, C.
    Duyster, J.
    Siveke, J. T.
    Dechow, T.
    ONCOGENE, 2015, 34 (05) : 578 - 588
  • [35] KRASG12D-driven pentose phosphate pathway remodeling imparts a targetable vulnerability synergizing with MRTX1133 for durable remissions in PDAC
    Jiang, Xiangyan
    Wang, Tao
    Zhao, Bin
    Sun, Haonan
    Dong, Yuman
    Ma, Yong
    Li, Zhigang
    Wu, Yuxia
    Wang, Keshen
    Guan, Xiaoying
    Long, Bo
    Qin, Long
    Shi, Wengui
    Shi, Lei
    He, Qichen
    Liu, Wenbo
    Li, Mingdou
    Xiao, Lixia
    Zhou, Chengliang
    Sun, Hui
    Yang, Jing
    Guan, Junhong
    Zhou, Huinian
    Yu, Zeyuan
    Jiao, Zuoyi
    CELL REPORTS MEDICINE, 2025, 6 (02)
  • [36] Deficiency in hormone-sensitive lipase accelerates the development of pancreatic cancer in conditional KrasG12D mice
    Mu Xu
    Hui-Hua Chang
    Xiaoman Jung
    Aune Moro
    Caroline Ei Ne Chou
    Jonathan King
    O. Joe Hines
    James Sinnett-Smith
    Enrique Rozengurt
    Guido Eibl
    BMC Cancer, 18
  • [37] Deficiency in hormone-sensitive lipase accelerates the development of pancreatic cancer in conditional KrasG12D mice
    Xu, Mu
    Chang, Hui-Hua
    Jung, Xiaoman
    Moro, Aune
    Chou, Caroline Ei Ne
    King, Jonathan
    Hines, O. Joe
    Sinnett-Smith, James
    Rozengurt, Enrique
    Eibl, Guido
    BMC CANCER, 2018, 18
  • [38] Combination of RAS(ON) Multi-Selective and G12D-Selective Inhibitors Improves Antitumor Activity and Enhances Antitumor Immunity in Preclinical Models of KRASG12D-Driven Cancers
    Jiang, L.
    Menard, M.
    Weller, C.
    Burnett, G. L.
    Maldonato, B.
    Wang, Z.
    Steele, S. L.
    Flagella, M.
    Evans, J. W.
    Morton, V.
    Ganesh, S.
    Chin, S.
    Mu, Y.
    Knox, J. E.
    Gill, A.
    Smith, J. A.
    Wildes, D.
    Singh, M.
    Quintana, E.
    Jiang, J.
    EUROPEAN JOURNAL OF CANCER, 2024, 211 : S113 - S114
  • [39] The PI3K-AKT-mTOR axis persists as a therapeutic dependency in KRASG12D-driven non-small cell lung cancer
    McDaid, W. J.
    Wilson, L.
    Adderley, H.
    Martinez-Lopez, A.
    Baker, M. J.
    Searle, J.
    Ginn, L.
    Budden, T.
    Aldea, M.
    Marinello, A.
    Aredo, J. V.
    Viros, A.
    Besse, B.
    Wakelee, H. A.
    Blackhall, F.
    Castillo-Lluva, S.
    Lindsay, C. R.
    Malliri, A.
    MOLECULAR CANCER, 2024, 23 (01)
  • [40] Germline Brca2 Heterozygosity Promotes KrasG12D -Driven Carcinogenesis in a Murine Model of Familial Pancreatic Cancer
    Skoulidis, Ferdinandos
    Cassidy, Liam D.
    Pisupati, Venkat
    Jonasson, Jon G.
    Bjarnason, Hordur
    Eyfjord, Jorunn E.
    Karreth, Florian A.
    Lim, Michael
    Barber, Lorraine M.
    Clatworthy, Susan A.
    Davies, Susan E.
    Olive, Kenneth P.
    Tuveson, David A.
    Venkitaraman, Ashok R.
    CANCER CELL, 2010, 18 (05) : 499 - 509