Recent advances in cellulose, pectin, carrageenan and alginate-based oral drug delivery systems

被引:39
|
作者
Raghav, Neera [1 ]
Vashisth, Chanchal [1 ]
Mor, Nitika [1 ]
Arya, Priyanka [1 ]
Sharma, Manishita R. [1 ]
Kaur, Ravinder [1 ]
Bhatti, Surender P. [2 ]
Kennedy, John F. [3 ]
机构
[1] Kurukshetra Univ, Chem Dept, Kurukshetra 136119, Haryana, India
[2] Dyal Singh Coll, Dept Chem, Karnal, India
[3] Chembiotech Labs Ltd, Tenbury Wells WR15 8FF, England
关键词
Drug delivery system; Natural polymers; NANOCOMPOSITE HYDROGEL BEADS; PH-SENSITIVE NANOCOMPOSITE; OXIDE BIO-NANOCOMPOSITE; GRAFTED GRAPHENE OXIDE; IN-VITRO EVALUATION; KAPPA-CARRAGEENAN; CONTROLLED-RELEASE; BACTERIAL CELLULOSE; COMPLEX NANOPARTICLES; SUSTAINED-RELEASE;
D O I
10.1016/j.ijbiomac.2023.125357
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Polymers-based drug delivery systems constitute one of the highly explored thrust areas in the field of the medicinal and pharmaceutical industries. In the past years, the properties of polymers have been modified in context to their solubility, release kinetics, targeted action site, absorption, and therapeutic efficacy. Despite the availability of diverse synthetic polymers for the bioavailability enhancement of drugs, the use of natural polymers is still highly recommended due to their easy availability, accessibility, and non-toxicity. The aim of the review is to provide the available literature of the last five years on oral drug delivery systems based on four natural polymers i.e., cellulose, pectin, carrageenan, and alginate in a concise and tabulated manner. In this review, most of the information is in tabulated form to provide easy accessibility to the reader. The data related to active pharmaceutical ingredients and supported components in different formulations of the mentioned polymers have been made available.
引用
收藏
页数:20
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